A Stochastic Model with Antigenic Diversity Threshold Using Largest Order Statistics
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 11
Abstract
Abstract: In the study of HIV infection and AIDS, one of the important aspects of investigation is the estimation of time to cross antigenic diversity threshold of HIV infected. The estimation of time to cross antigenic diversity threshold over the time interval (0, t] is an important aspect which help medical intervention. We propose the stochastic model assuming the intercontact time between successive contact from a largest order statistics and threshold distribution is Generalized Rayleigh distribution. The expected time to seroconversion and its variance are derived and numerical illustration is also given using simulated data. Keywords:Antigenic Diversity, Threshold, Acquired Immuno Deficiency Syndrome, Human Immunodeficiency Virus, Largest Order Statistics, Seroconversion
Authors and Affiliations
Kannan R, , Iyappan M
Keywords
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