A STUDY EVALUATING APPROPRIATENESS OF UTILIZATION PATTERN OF ANTIMICROBIALS IN PATIENTS ADMITTED IN MEDICAL INTENSIVE CARE UNIT OF TERTIARY CARE TEACHING RURAL HOSPITAL
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 5
Abstract
Objectives: To evaluate the appropriateness of utilization pattern of antimicrobials in the intensive care unit of a tertiary care teaching rural hospital.Methods: This prospective and observational study was carried out in 500 patients admitted to the intensive care unit (ICU) who was prescribed antimicrobial agents, between October 2011 and May 2013. All patients were followed up throughout their stay. A study was carried out to study the appropriateness of utilization pattern of antimicrobials in the medical ICU.Results: The dosage form of the prescribed antimicrobial was most appropriate. Most common route of drug administration was intravenous and it was most appropriate. Dose of drugs chosen was acceptable and the frequency of administration of antimicrobials was also acceptable. However, in 47 patients change of antimicrobials following initial empirical therapy was done without CST which was inappropriate. The appropriateness score calculated using structured, semi scientific, arbitrary 20 point appropriateness scale, was 15.48. The score, 15.48, fell in the category of appropriate use and the use of antimicrobials was found to be appropriate.Conclusion: To prevent antimicrobial resistance, rational use of antimicrobials is a must. The concept of prescribing antimicrobial drugs for every patient should be abolished. Antimicrobial policy should be developed and it must be ensured that it is implemented. Antimicrobial stewardship should also be implemented to prevent the emergence of resistance.Â
Authors and Affiliations
Ravi R Alamchandani, Pooja R Khubchandani
Keywords
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