A study of clinical features and factors associated with patients of liver failure at tertiary health care center
Journal Title: Medpulse International Journal of Medicine - Year 2017, Vol 4, Issue 3
Abstract
Background: Chronic liver diseases (CLD) cause significant morbidity and mortality worldwide. Multiple etiological factors lead to a similar clinico-pathological syndrome in CLDs, although the rates of progression and clinical course may be different Aims and Objectives: To Study Clinical features and factors associated with Patients of Liver failure at tertiary health care center. Methodology: After approval from institutional ethical committee a cross-sectional study was carried out in the department of tertiary health care center during two-year period i.e. January 2008 to January 2010 in the patients who were diagnosed as patients of Liver. All the details of the patients like clinical features and Associated factors was retrieved from patients. All the serological investigations like HBS, HCV, HEV, USG for fatty liver cirrhosis, LFT for liver function was done. The statistical analysis done by Linear correlation by SPSS version 19 software. Result: In our study we have seen that the majority of the patients were in the age group of 60-70 were 38.03%, followed by 50- 60 were 29.58%, 40-50 were 23.94%, 30-40 were 7.04% and 20-30 were 1.41%. The increase in the trend of the patients as per age was statistically significant (P<0.002, r=0.98). The majority of the patients were Male i.e. 66.20% followed by Female 33.80%. The most common clinical features were Decreased appetite were 90%; followed by Jaundice in 85%, Gastrointestinal bleeding in 68%, Peripheral edema in 56%, Encephalopathy in 45%. The most common Clinical signs were Loss of body hair in 85% followed by Spider angioma in 70% Gynecomastia in 60%. Parotid enlargement in 55%, Splenomegaly in 40%. The most common associated factors were Alcoholic Liver Disease - 56%, HBV-40%, HCV - 29%, NAFLD- 21%, Diabetes -17%, Chronic NSAID use-12%. Conclusion: It can be concluded from our study that the most common associated factors in our study were Alcoholic Liver Disease, HBV, HCV, NAFLD, Diabetes, Chronic NSAID use and increasing age. These associated factors is useful for the prevention and treatment of patents of Liver failure
Authors and Affiliations
Mahendra N Sonwane, Vidyadhar G Maske
Keywords
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