A Study of Clinico bio chemical profile of the patients admitted with OP poisoning at tertiary health care centre
Journal Title: Medpulse International Journal of Medicine - Year 2018, Vol 6, Issue 2
Abstract
Abstract Background: The pesticide poisoning like Organophosphorus (OP) is attributed for the death of around 200,000 people each year, largely in the Asia-Pacific region. Aims and Objectives: to Study Clinico bio chemical profile of the patients admitted with OP poisoning at tertiary health care centre. Methodology: After approval from institutional ethical committee a cross-sectional study was carried out in the patients with history of ingestion of Organo phosphorus compounds (OP), accidental or suicidal brought to casualty or admitted to the department of Medicine during the one year period i.e. March 2016 to March 2017.The severity of poisoning was determined by Pseudo cholinesterase level Severe (≤700 IU), Moderate (701-14,00 IU), Mild (1401-3500 IU), Latent (>3500 IU) . The statistical analyses done by Chi –square test calculated by SPSS 19 version software. Result: In our study we have seen that The majority of the patients were in the age group of 30-40 i.e. 28.36% , followed by 40-50, 25.37%, 50-60 were 19.40%, >60 were 16.42%, 20-30 were 10.45%. The majority of the patients were Male i.e. 55.22% followed by Female i.e. 44.78%. The most common symptoms were Impaired , blurry vision -90%, Excess saliva-85%, Muscle weakness-75%, Dizziness -72%, Coughing and wheezing-68%, Difficulty in breathing-32%, Muscle twitching and tremor-29%, Irregular heartbeat-21%, Respiratory depression -19%. The majority of the patients with severe type of poisoning were having poor outcome or death i.e. 57.89 % as compared to Recovered were 42.62%, in Moderate- the Death or Poor outcome was 31.82 % and Recovered were 68.18%, in Mild Death or Poor outcome were 10.53 % and Recovered were 89.47%, in Latent it was -Death or Poor outcome 0% and 100% recovered. This difference of mortality with respect to severity of poisoning on Pseudo cholinesterase level was statistically significant (X2=14.62,df=3,p<0.002). Conclusion: It can be concluded from our study that The majority of the patients were in the age group of 30-40, most common symptoms were Impaired, blurry vision , Excess saliva, Muscle weakness, Dizziness , the pseudo-choline esterase level significantly associated with the poor outcome or mortality in the patients .
Authors and Affiliations
Manish Pendse
Keywords
Related Articles
- EP ID EP464237
- DOI 10.26611/1021622
- Views 66
- Downloads 0
A clinical profile and factors associated with swine flu patients at tertiary health care centre
Background: Swine flu (Swine Influenza) pandemic of 2009 was started by swine origin Influenza A virus subtype H1N1 virus strain. Pregnant individuals, children under 2 years of age, young adults, and individuals with an...
A cross sectional study on the assessment of cardiac autonomic dysfunctions among patients with type 2 diabetes mellitus
Background: Neuropathy is a common complication of diabetes mellitus. It may affect both peripheral and autonomic nervous system. The objective of the present study was to investigate the prevalence of cardiac autonomic...
Outcome of pneumonia among the patients: A retrospective hospital based study
Background: Pneumonia is an infection caused primarily by bacteria or viruses and less commonly by fungi and parasites. More than 100 strains of infectious agents have been identified but only a few of them are responsib...
Gender impact in diabetic patients with acute myocardial infarction: A hospital-based study
Objective: There are previous studies stating gender differences in clinical profile in diabetics who sustain acute myocardial infarction. This study was undertaken to observe such differences in a small cohort of popula...
A study 50 cases of clinical outcome and analysis of cases of snake bite admitted at P.D.U. hospital
Background: Snake bite has become a very important preventable public health hazard. Snake bite usually take place in villages and forests. About 2 million people are bitten by snake and about 35000-50000 cases prove fat...