A study of congenital anomalies of human adult cadaveric kidneys
Journal Title: MedPulse -International Medical Journal - Year 2015, Vol 2, Issue 6
Abstract
Aim: The present study was undertaken to observe and study the congenital anomalies of the human adult cadaveric kidneys. Material and Methods: Forty human adult cadavers over a period of two years from the department of Anatomy, J.N. Medical College, Belagavi, were included in this study. Congenital anomalies of kidneys were observed and studied during routine dissections. Observations: Congenital anomaly like unilateral absence of kidney was found in one cadaver. Also we found unilateral lobulated kidney in six cadavers. Embryological basis: The metanephric buds begin to develop into kidneys in the fifth week of gestation. Failure of development of metanephric buds leads to renal agenesis. Renal agenesis is closely associated with ipsilateral congenital anomalies of genito-urinary system, cardiac and skeletal systems. The unilateral renal agenesis has also been reported to be associated with X-linked dominant trait, Kallmann’s syndrome, chromosomal abnormalities as trisomy 21, trisomy 22, trisomy 7 etc. Persistant fetal lobulations occurs due to incomplete fusion of the developing renal lobules. Conclusion: Patients with unilateral renal agenesis and a normal solitary kidney are at increased risk of proteinuria, hypertension, and renal insufficiency. Therefore, it is essential to have prolonged and careful follow-up and to employ strategies that maximize renal preservation. Often, persistant fetal lobulated kidney is a normal variation, but it should be distinguished from inflammatory scarring of the kidney, renal infarcts and tumours, which it can mimic as a pseudotumour. The knowledge of these anomalies will help the clinicians during the procedures of kidney.
Authors and Affiliations
Manisha S More, Manoj D Togale, Shilpa Bhimalli, Daksha Dixit, S P Desai
Keywords
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