A Study of Dexmedetomidine Vs Tramadol for Post Operative Analgesia in Patients Undergoing Spine Surgeries.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 3
Abstract
Background: Spinal procedures are generally associated with intense pain in the initial postoperative period. Adequate pain management in this period has been seen to correlate well with improved functional outcome, early ambulation, early discharge, and preventing the development of chronic pain. A multiple array of pharmacological options exists for the effective treatment of post spinal surgery pain, but each of these drugs possesses inherent advantages and disadvantages which restricts their universal applicability. In this study, we aim to evaluate and compare the analgesic effects of Dexmedetomidine and Tramadol in patients who are undergoing spine surgeries. Materials and Methods: 50 patients posted for elective lumbar laminectomy and discectomy under general anesthesia were included in the study. Randomization was done using the sealed envelope technique; accordingly patients were allotted to group D (for dexemedetomidine) and group T (Tramadol) with 25 patients each. We evaluated the analgesic efficacy , pain intensity and quantify the requirement of rescue analgesia in the postoperative period in the two groups, hemodynamics in peri-operative period in patients using dexmedetomidine and tramadol for postoperative analgesia in spine surgeries. Results: Comparison of intraoperative heart rate of both groups showed that there were no statistically significant differences in heart rates between the two groups (p value > 0.05). Comparison of intraoperative systolic blood pressure of both groups showed that there were no statistically significant differences in systolic blood pressure between the two groups. (p value > 0.05) . Comparison of intraoperative diastolic blood pressure of both groups showed that there were no statistically significant differences in diastolic blood pressure between the two groups. (p value >0.05) . Comparison of intraoperative Mean arterial blood pressure of both groups showed that there were no statistically significant differences in systolic blood pressure between the two groups. (p value > 0.05) . Comparison of intraoperative oxygen saturation of both groups showed that there were no statistically significant differences in oxygen saturation between the two groups. (p value > 0.05) . Comparison of VRS pain score in both group showed that it was statistically significant at 3,4,5,6,7,8,9,10 hours in the tramadol group,p value in these hours were < 0.05 . First dose rescue analgesic requirement were comparable on both the groups and was found statistically significant at 8 hour-3 patients (12%) in tramadol group required rescue analgesia and was found statistically significant . Conclusion: Dexmedetomidine has superior analgesic efficacy when compared to tramadol in patient undergoing spine surgeries.
Authors and Affiliations
K. Poojitha
Keywords
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