A Study of Effect of Different Donor Parameters on single donor platelet apheresis in central India Tertiary care hospital
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 1
Abstract
Introduction: Use of single donor platelets (SDP) has increased by radical change over past few years. SDP not only increase the quality of product in terms of decreased cellular contamination but also increases the overall yield of platelet collected. However various donor parameter exert their effect on yield of single donor platelet apheresis. Materials and Methods: The present study included the outcome of 65 SDPA procedures that were conducted on Haemonetics MCS+ intermittent flow cell separator (Haemonetic Corporation). It employs single venous access utilizing closed collection apheresis kits with efficient leukoreduction. Study was undertaken at blood bank M.Y. Hospital associated with M.G.M. Medical College, Indore, and a tertiary care Central Government Teaching Institute. Results: The mean platelet yield was 2.7± 0.83(1.6-4.9 × 1011/µl).Platelet yield showed high statistical significance with pre donation platelet count (p =0.000). Other than pre donation platelet counts, SDP yield also showed statistical significant correlation with weight and MPV. However no statistical significance was seen height (p=0.838), Hemoglobin (p=0.554) pre donation WBC count (p=0.052) and PDW (p=0.963) of donor on platelet yield. Conclusion: Hence, in our study, we found platelet yield showed positive statistical significance with pre donation platelet count as well as with pre donation weight and MPV. To find out interventions that could increase pre donation platelet would have a positive effect on platelet product yields
Authors and Affiliations
Dr Priyanka Solanki
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