A STUDY OF ELECTROCARDIOGRAPHIC, ECHOCARDIOGRAPHIC AND HAEMATOLOGICAL FINDINGS IN CHRONIC OBSTRUCTIVE LUNG DISEASE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 42
Abstract
BACKGROUND Chronic Obstructive Pulmonary Disease (COPD) has been defined as a disease state characterised by airflow limitation that is not fully reversible.1 The GOLD guidelines define COPD as- “A preventable and treatable disease with some significant extrapulmonary effects that may contribute to the severity in the individual patient. Its pulmonary component is characterised by airflow limitation that is not fully reversible. The airflow limitation is usually progressive and associated with an abnormal inflammatory response of the lung to noxious particles or gases.” 2 COPD is the fourth leading cause of death and affects > 16 million persons in the United States. COPD is also a disease of increasing public health importance around the world. GOLD estimates suggest that COPD will rise from the sixth to the third most common cause of death worldwide by 2020. In India, COPD is the 2nd most common lung disorder after pulmonary tuberculosis. 3 The disease is frequently encountered in the middle-aged patients and is rare below the age of 35. It affects males more than females. It is equally prevalent in rural and urban areas.3 MATERIALS AND METHODS The present study was a cross-sectional descriptive study, conducted in Department of Pulmonary Medicine in ID Hospital, Guntur. 100 COPD patients who were attending OP were included in the study. The study period was January 2015 to June 2016. The data was analysed using SPSS (Statistical Package for Social Sciences) version 20. Results were expressed in terms percentage, means, proportions and standard deviation and Chi-square test were applied and p < 0.05 was considered as statistically significant. RESULTS The present study included 100 patients with stable chronic obstructive pulmonary disease attending Department of Pulmonary Medicine, GGH, Guntur. After satisfying the inclusion and exclusion criteria, the haematological findings, ECG findings and Echocardiac findings are studied and compared with other studies. CONCLUSION The lung function parameters namely FEV1% has significant inverse relation between the severity of COPD, progressively decreasing with the increasing severity. On electrocardiography, the most common abnormality observed was ‘P’ pulmonale, but R/S ratio in V6 < 1 associated significantly with the severity of COPD. In the Echocardiographic study, the right heart parameters were significantly increased in Mild, Moderate and Severe and Very Severe COPD respectively. Our study emphasises the importance of haematological parameters namely Hb% and PCV, were significantly increased in Mild, Moderate and Severe and Very Severe Chronic Obstructive Pulmonary Diseases respectively.
Authors and Affiliations
Seshagirirao D, Thriveni M
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