A study of intradermal testing with aeroallergens in patients with chronic urticaria in a tertiary care centre
Journal Title: MedPulse -International Medical Journal - Year 2016, Vol 3, Issue 4
Abstract
Background: Chronic urticaria affects upto 1% of the population, and in most cases lesions occur spontaneously without an obvious identifiable external cause. Numerous articles have been published citing the role of aeroallergens in chronic urticaria. Proper controlled trials delineating the pattern of aeroallergen sensitivity and defining its association with the disease are lacking Aim: To find out a possible association between aeroallergen sensitivity and cases of chronic urticaria in which no cause was identified after assessment with a standard protocol. Methods: The sensitivity of chronic urticaria patients to a panel of locally prevalent 35 aeroallergens was studied using intradermal method. Results: 90% of patients showed one or more significant positive reaction to the allergens tested and the average number of positive reactions to intradermal tests per person was 11.25. There was no statistically significant difference between the number of positives in dust aggravated and non-dust aggravated urticaria and between men and women. Positivity among different groups of aeroallergens were as follows: insects-86%, pollen-72%, fungi-72% and 42% in the wool, dander and feather group. Among the insects group all individual allergens had high positivity rates, the maximum being for housefly. Limitations: The limitation of the study was the small sample size and the absence of control group. Conclusions: Majority of chronic urticaria patients had sensitivity to one or more tested antigens, the maximum sensitivity being for insects.
Authors and Affiliations
Bindurani S, Umadevi C S, C Ravindranhetan, Najeeba Riyaz, Mohamed Musthafa
Keywords
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