A STUDY OF LIPID PROFILE IN CHRONIC ALCOHOLICS
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 26
Abstract
BACKGROUND There are about 2 billion people worldwide who consume alcoholic beverages. Alcohol causes 1.8 million deaths worldwide. Alcohol consumption has both health and social consequences via intoxication, alcohol dependence and other biochemical effects of alcohol. There is increasing evidence that both volume of alcohol and pattern of drinking is relevant for health outcomes. Alcohol is known to cause various types of malignancies (including oesophageal, liver), cirrhosis of liver, homicide, epileptic seizures and motor vehicle accidents. There is increasing research in the past decades about the role of alcohol both as a risk and as a protective factor for cardiovascular disease. Beneficial effects of alcohol in coronary heart disease is seen at low to moderate levels of average volume of alcohol consumption. The concept nowadays is that average volume of drinking and coronary artery disease shows a J shaped relationship with detrimental effects compared with abstainers at higher levels of alcohol intake. Lower levels of alcohol consumption appear to protect against coronary artery disease by favorable lipid profile i.e. an increase in HDL level and decrease in LDL level. The present study aims to study the relationship between levels of alcohol consumption and fasting lipid levels. The aim of the study is to compare and correlate values of fasting lipid levels in moderate and heavy alcohol consumers with non-alcohol consumers. MATERIALS AND METHODS This study is a case-control study. The study is done over a 2-year period. Total 150 subjects were taken, both cases (100) and controls (50). Subjects are divided into 3 groups, moderate and heavy alcohol consumers and non-alcohol consumers. Detailed history was taken, and clinical examination done as per proforma. They underwent fasting lipid profile. These lipid values were compared with each other in all the 3 groups using standard statistical methods. RESULTS Average level of total cholesterol was lowest in moderate alcohol consumers (169) when compared to non-alcohol consumers (185) and heavy alcohol consumers (217). Serum Triglyceride levels and LDL levels were also lowest in moderate alcohol consumers when compared to both abstainers and heavy alcohol consumers. Average value of Serum HDL levels was highest in moderate alcohol consumers (45), when compared to non-alcohol consumers (40) and heavy alcohol consumers (34). Moderate Alcohol consumption showed a favourable lipid profile when compared to abstainers and more so when compared with heavy alcohol consumers. CONCLUSION Moderate alcohol consumption is associated with favourable lipid profile (low LDL, Low Total cholesterol and Triglyceride levels and high HDL levels), which is a protective factor for coronary artery disease.
Authors and Affiliations
Ganga Prasad U. , Katragadda Harish
Keywords
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- EP ID EP567137
- DOI 10.18410/jebmh/2018/409
- Views 75
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