A study of magnesium supplementation on sensory nerve conduction velocity (N.C.V) in patients of diabetic neuropathy
Journal Title: Indian Journal of Clinical Anatomy and Physiology - Year 2018, Vol 5, Issue 3
Abstract
Introduction Globally diabetes is the leading known cause of neuropathy In type 2 diabetes mellitus neuropathy being the most common complication contributes to majority of morbidity and mortality in such patients Hyperglycemia is the main risk factor for diabetic neuropathy A positive association exists between low serum magnesium levels and symptoms characteristics of peripheral neuropathyMaterials and Methods The study was done in 60 diabetic neuropathy patients attending the neurology OPD of SN Medical College hospital between February 2009 to August 2010 These patients were divided into two groups Group I n30 receiving magnesium and metformin therapy for a period of 16 weeks Group II n30 receiving only metformin therapy The blood samples were collected and analyzed for serum magnesium at 0 4 8 16 weeks respectively Nerve conduction velocity for common peroneal nerve was done at 0 4 8 16 weeks respectively Average of males in group 1 was 5436118yrs and of females was 5309147yrs and in group II was 5594162yrs and of females was 5283158yrs respectivelyResults In Group I mean baseline value for sensory NCV of sural nerve is 4223076 and after treatment values at 4 weeks is 4685099 8 weeks 4957108 at 16 weeks 5062085 respectively The difference between before and after treatment was extremely significant in Group I In Group II mean Baseline value for sensory NCV of Sural N is 4289063 and after treatment values at 4 weeks is 4374063 8 weeks 44131061 and at 16 weeks 4453062 respectively Statistically insignificant difference was observed in group II patients for sensory nerve conduction velocity before and after treatment values at 16 weeks p005Conclusion Magnesium supplementation along with regular anti diabetic therapy improves sensory nerve conduction velocityKeywords Diabetic neuropathy Magnesium supplementation Sensory nerve conduction velocity
Authors and Affiliations
Ashutosh Bhardwaj, Pooja Chaurasia, Arun Chaturvedi
Keywords
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- EP ID EP476104
- DOI 10.18231/2394-2126.2018.0086
- Views 58
- Downloads 0
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A study of magnesium supplementation on sensory nerve conduction velocity (N.C.V) in patients of diabetic neuropathy
Introduction Globally diabetes is the leading known cause of neuropathy In type 2 diabetes mellitus neuropathy being the most common complication contributes to majority of morbidity and mortality in such patients Hyperg...