A study of serum lipid profile among obese and non-obese individuals with or without Type-II Diabetes Mellitus
Journal Title: MedPulse -International Medical Journal - Year 2014, Vol 1, Issue 6
Abstract
Introduction: Diabetes is a group of metabolic diseases characterized by high blood glucose levels while obesity is accumulation of excess body fat. Diabetes and obesity currently threaten the health, well being and economic welfare of humanity. Today, 90% of over 150 million people suffering from Diabetes worldwide have Type-II Diabetes Mellitus while over 300 million are obese. Thus, up to 1.7 billion of the world’s population is at an increased risk of heart attack and stroke. Objectives: To study and compare the lipid profile among obese and non-obese individuals with or without Type-II Diabetes Mellitus. Methodology: The Body Mass Index (BMI), Fasting Blood Glucose (FBG) and Lipid profile were studied using standard bio-chemical methods. Both obese and non-obese male and female individuals in the age group of 30-70 yrs with or without Type-II Diabetes Mellitus were included. Results and Discussion: The FBG was significant with a mean of (166.66±69.51) in obese and non-obese Diabetics and (108.63±42.44, P<0.0001) in controls. Total cholesterol (TC) mean (183.7±42.58) in cases and (185.71±40.66, P=0.7919) in controls, Triglycerides (TG) mean (180.18±116.87) in Diabetics compared to (185.75±219.39, P=0.8625) in controls, HDL-C mean (43.83±8.74) in Diabetics, compared to (45.58±8.41, P=0.7656) in controls and LDL-C (109.39±28.01) in Diabetics and (110.92±28.08, P=0.7656) in controls. The BMI mean was (28.415±3.822) in Diabetics, compared to (27.103±4.34, P=0.0815) in controls. Male obese patients had significant mean of FBG with (124.77±32) than females (199.25±78.56, P=0.0112) and there was no significant changes in lipid parameters between male and females, TC (P=0.9011), TG (P=0.0812). These findings indicate that lipid parameters can be used for Diabetic patients in the early diagnosis of dyslipidemia and timely intervention with lipid lowering drugs.
Authors and Affiliations
Mamatha V, H. V. Shetty, Usha S. M. R, Priyadarshini K. S, Deepa. M.
Keywords
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