A Study of Spectrum and Prevalence of Anaemia in Patients of Decompensated Chronic Liver Disease in a Rural Tertiary Care Centre in North India
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 5
Abstract
Abstract: Anaemia is a frequently observed manifestation during clinical course of chronic liver disease. This study was planned to assess the prevalence and spectrum of anaemia in decompensated chronic liver disease patients in a rural tertiary health care centre in north India. One hundred patients were selected in random for this study, from patients coming to department of general medicine OPD and ward patients. Patients of liver disease whose symptoms and signs persisted for more than six months and having signs of decompensated liver disease like ascitis, Variceal bleeding and hepatic encephalopathy were included in the study. Alcoholic, post infective, metabolic causes of liver diseases were taken into consideration. The patients underwent relevant investigations to find the severity and typing of anemia. The mean age of the patients was 44±14 years. The male/female ratio was 4.9/1.The mean Hb value was 9.5±1.92g/dl. The mean MCV was 89.2±11.02fl. 87% patients of decompensated chronic liver disease in our study were anaemic.20 males (24.1%) and 5 females (29.4%) of the patients had severe anaemia. 24 males (28.9%) and 6 females (35.3%) had moderate anaemia.27 males (32.5%) and 5 females (29.4%) had mild anaemia.12 males and 1 female had normal Hb level. Normocytic Normochromic anaemia was more prevalent than other types of anaemias. 43.7 % of the anaemic patients revealed normocytic normochromic picture, followed by microcytic hypochromic (28.7%) and macrocytic(25.3%) while 2.3 % patients had dimorphic picture. 28 males (39.4%) and 10 females (62.5%) had normocytic normochromic anaemia.21 males (29.4%) and 4 females (25%) had microcytic hypochromic anaemia. 20 males (28.2%) and 2 females (12.5%) had macrocytic anemia. In this study, 14 patients were positive for HBsAg and 13 were positive for Anti HCV. All 20 males having macrocytic anaemia gave history of chronic alcoholism.
Authors and Affiliations
Dr. Tarun, Ravinder Pal, Navtej Singh, Rashi Bhareja, Ramesh Verma, Chiranjeev Kumar Gathwal
Keywords
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