A Study of Spectrum of Skin Adnexal Tumors in Ajmer Region
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 5
Abstract
Introduction: The adnexa are part of the skin and are composed of different kinds of cells that can give rise to a wide variety of tumors. It is comprised of sweat glands, sebaceous glands and hair follicles, all of which share the same origin. Although most of these tumors are benign, it is important to diagnose them accurately since many of such tumors are genetically predetermined. The aims of this work are to determine the spectrum of histopathological patterns of Adnexal tumors of skin, to characterise the tumors histologically according to World Health Organization (WHO) classification. Materials and Methods: The study was carried out in Department of Pathology, JLN Medical College, Ajmer and Associated group of Hospitals, both retrospective (July 2013 to June 2014) and prospective (July 2014 to June 2016) over a period of 3 years In this study biopsies received in 10% buffered formalin were processed and slides were stained with routine H & E stain and special stains done wherever needed. Results: A total of 50 cases of Skin Adnexal Tumors (SAT) were studied during the study period which were classified into different groups. 47(94%) cases were benign and only 3(6%) cases were malignant. Out of 50 SAT’s hair follicle tumors 22 cases (44%) were the most common and the least common were tumors with sebaceous differentiation 9 (18%) cases. Most common SAT was nodular hidradenoma 13cases (26%). Among malignant adnexal tumors there were 1 (2%) case each of sebaceous carcinoma, microcystic adnexal tumor and paget’s disease Most common age group affected range from 41-50 years (11 cases) and least common age was above 80 years. Skin adnexal tumors are more common in females than males (M:F ratio 20:30) . Clinicopathological correlation was found in 20(40%) cases while in 30(60%) cases histopathology gave the final diagnosis. Conclusion: Adnexal skin tumors have distinct histological patterns which differentiates them from other cutaneous tumors. Clinical diagnosis of adnexal tumors is extremely difficult because various adnexal tumors have similar clinical presentation and histopathological examination becomes essential in diagnosis.
Authors and Affiliations
Geeta Pachori, Manisha Jain, Soniya Sanadhya, Tushar Bayla
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