A Study Of The Clinical and Biochemical Profile Of Acute Viral Hepatitis
Journal Title: International Journal of Biomedical and Advance Research - Year 2015, Vol 6, Issue 10
Abstract
Aim: This study was performed to compare the clinical, biochemical and etiological properties of acute viral hepatitis (AVH) and to compare clinical and laboratory parameters of faeco-oraly transmitted hepatitis: hepatitis A+ hepatitis E (A+E) with hematologicaly transmitted: hepatitis B, C, D (B+C+D) hepatitis. Material and Methods: Biochemical and clinical data were collected from 40 patients with AVH. They were tested for hepatitis B surface antigen (HBsAg), IgM anti-Hepatitis A virus (HAV), IgM anti-HBc (hepatitis B core antigen), IgM anti- hepatitis D (HDV), or IgM anti- hepatitis C (HCV). Finally X2 test was used to analysis of data. Results: Most patients were young adults and presented with jaundice and other constitutional features, although anicteric hepatitis was also seen. Hepatitis E was the most common AVH. Malaise, fever, icterus, vomiting and nausea were significantly more in Hepatitis A +E compared with Hepatitis B + C in acute course. Serum bilirubin both total and direct was significantly elevated in hepatitis A + E compared with Hepatitis B + C in acute course. Conclusions: Hepatitis E was the most common AVH .There were some differences in clinical and laboratory findings regarding to the etiology but it does not necessarily distinguish one cause of hepatitis from another.
Authors and Affiliations
Varsha Shirish Dabadghao, Ram Barure, Suresh Kumar Sharma, Dr Sangram S Mangudkar
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