A STUDY OF THE CLINICAL PROFILE OF NEONATES WITH THROMBOCYTOPENIA
Journal Title: Stanley Medical Journal - Year 2016, Vol 3, Issue 3
Abstract
Introduction: In Neonatal Intensive Care Units, neonatal thrombocytopenia is the commonest haematological abnormality. Around 20-40% of neonates admitted to NICU will develop thrombocytopenia and 20% of them will develop severe thrombocytopenia. Subjects & methods: This is a retrospective study of 100 consecutive thrombocytopenic babies irrespective of their underlying illness admitted in the NICU of Government Dharmapuri Medical College Hospital, Dharmapuri from January’ 2014. Results: The study group was divided into two groups based on the severity of thrombocytopenia. There were 71 babies in group I and 29 babies in group II. The male: female sex ratio of the study population was 1.2:1. The study group consisted of 42% of term babies and 58% of preterm babies. Among the severely thrombocytopenic babies in the study group, 45% were term babies and 55% were preterm babies. Among the study group, 68 cases were born extramural. About 31% of preterm babies had severe thrombocytopenia. About half of the babies in the study group were below 2.5 kg. Maternal PIH was significantly associated with thrombocytopenia. Septicemia and Birth asphyxia were the predominant causes of thrombocytopenia in both the groups. In group I the prevalence of mucosal bleed was 12.6% whereas in group II it was 89.7%. The prevalence of septicemia was significantly high in both the groups. The incidence of severe thrombocytopenia was significantly high in gram negative sepsis. In the study group 5 neonates died and the proportion of mortality was significantly high in the severely thrombocytopenic infants. Conclusion: Septicemia and birth asphyxia were the common causes of neonatal thrombocytopenia. The easier and cost effective way to prevent thrombocytopenia and its death is by preventing the occurrence of sepsis and birth asphyxia.
Authors and Affiliations
Rameshbabu B, Kumaravel K. S
Keywords
Related Articles
- EP ID EP217046
- DOI -
- Views 117
- Downloads 0
Evaluation of efficacy of sonosalphingogram in evaluating tubal patency with hysterosalphingogram as gold standard
Aim: The objective of present study is to evaluate the efficacy of sonosalphingogram in evaluating patent tubes in infertility patients with hysterosalphingogram as gold standard. Materials and methods: Sonosalphingogr...
SPECTRUM OF ORAL AND DENTAL MANIFESTATIONS IN CHRONIC KIDNEY DISEASE PATIENTS
Due to increased survival among Chronic Kidney Disease(CKD) patients, new problems including concerns of oral health have appeared. AIMS O...
A case of adult onset Henoch Schonlein Purpura with mononeuropathy
Henoch Schonlein purpura (HSP) is characterized by leukocytoclastic vasculitis involving the small vessels with deposition of immune complexes that contain IgA. Clinical signs include purpura , arthralgia, glomerulonephr...
A CLINICAL AND ELECTROENCEPHALOGRAPHIC PROFILE OF FIRST UNPROVOKED SEIZURE IN ADOLESCENTS AND ADULTS IN A TERTIARY CARE CENTER
Context:A first unprovoked seizure is frightening experience both for the patient and family. Prognosis and treatment of the first unprovoked seizure depends on identification of specific epilepsy syndrome. Aims:To study...
PHARMACOVIGILANCE STUDY OF ANTIDEPRESSANTS -SELECTIVE SEROTONIN REUPTAKE INHIBITORS
AIMS: To find the incidence and pattern of adverse effects with selective serotonin reuptake inhibitors METHODS AND MATERIAL: Adverse effects data was collected using suspected adverse drug reaction monitoring form by ce...