A study on Catheter related bloodstream infections (CRBSI) in Intensive care unit patients in a tertiary care hospital
Journal Title: Indian Journal of Microbiology Research - Year 2017, Vol 4, Issue 2
Abstract
Introduction: Catheter related blood stream infections (CRBSI) independently increase hospital costs and length of stay. Knowledge about CRBSIs would help in improving infection control practices and managing nosocomial sepsis. Objectives:To study the prevalence of central venous catheter related blood stream infections and to identify clinical risk factors & the microbiological profile of organisms causing CRBSI. Materials & Methods: This was a prospective observational study carried out in the medical ICU of Chettinad Hospital and Research Institute, over a period of one year from March 2014 to February 2015. All adult non-immunocompromised patients admitted to the Intensive care unit(ICU), who had a non-tunnelled Central venous catheter(CVC) insertedwere included. Blood cultures were taken at the time of CVC insertion. At the time of removal, catheters were cultured using semi-quantitative method(SQC) of Makialong with a paired peripheral blood culture. The incidence of BSI was measured per 1000 CVC days. Results: A total of 82 patients with a cumulative 434 CVC days were included. Of this, 17 catheters (20.73 %) were positive for SQC. 3 patients (17.6%) had developed CRBSI, and the same organism with identical antibiogram pattern was isolated from both the blood and CVC tip. 10 patients (58.8%) had only catheter associated infection without bacteremia. 4 patients(23.5%) had positive blood cultures with different organism growing in CVC tip. CRBSI rate was 6.5/1000CVC days. The risk factors were diabetes mellitus, central line in situ for more than 7 days and emergency insertions. Out of the three definite CRBSIs, two patients grew Klebsiella pneumoniae and one patient grew Staphylococcus epidermidis. Of the 17 CVC tips which yielded positive growth, 53% were CoNS, followed by Klebsiella pneumoniae, E.coli, Enterococcus spp and Candida. CoNS was penicillin resistant and vancomycin sensitive. Majority of Klebsiella pneumoniae isolates were ESBL producers. Conclusion: The knowledge of incidence of CRBSI and the microbiological spectra will be useful in formulating bundles of care and effective programs to control hospital acquired infections.
Authors and Affiliations
Abirami E, Preethi Venkatesan, Priyadarshini Shanmugam, Shameem Banu Abdul Sattar
Keywords
Related Articles
- EP ID EP294235
- DOI 10.18231/2394-5478.2017.0029
- Views 60
- Downloads 0
Bacteriology and antimicrobial susceptibility pattern of external ocular infections in rural tertiary care teaching hospital
Background: This study was aimed at determining the prevalence of external ocular infections and susceptibility profile of associated bacteria along with special reference to methicillin-resistant Staphylococcus aureus (...
Multivariate analysis of risk factors for ESBL and AmpC producing Escherichia coli and Klebsiella pneumoniae at a Tertiary Care Hospital in Karnataka: A case control study
Introduction Extended spectrum betalactamase ESBL and AmpC producing organisms pose unique challenges to clinical microbiologists clinicians infection control professionalsThe objective of the present study was to analyz...
Resident microbial flora amongst nursing staff as a source of nosocomial infection
Background: Infections due to hospital-acquired microbes is an evolving problem worldwide. Prevalence as high as 19%, of these infections in developing countries poses a challenge to health care providers. A major source...
Incidence of extended spectrum beta lactamase producing Escherichia coli and Klebsiella pneumoniae from faecal samples in patients and healthy subjects
Faecal carrier rates of extended spectrum beta lactamase (ESBL) producing Escherichia coli and Klebsiella pneumoniae were analysed in 138 inpatients, 126 outpatients and 216 healthy individuals. Overall faecal carriage o...
Microbiological profile of ventilator-associated pneumonia in the intensive care unit of a tertiary hospital in Visakhapatnam, India
Introduction: Ventilator-associated pneumonia (VAP) is defined as pneumonia occurring more than 48 hours after the initiation of endotracheal intubation and it is the most common nosocomial infection in the intensive car...