A Study on Correlation between Microalbuminuria and Ultrasonographically Measured Carotid Artery Intima Media Thickness In Type 2 Diabetes Mellitus Subjects.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 1
Abstract
Background: This study was done to find out the correlation between micro albuminuria and carotid artery intima media thickness, an early marker of atherosclerosis in type 2 diabetic subjects. Methods: 100 patients including male and female with age more than 40 years type 2 DM having microalbuminuria or not were included in this study based upon the inclusion & exclusion criteria. Detailed history physical examinations & relevant systemic examinations& routine investigations were done as per structured proforma & data were analyzed with appropriate statistical tests and methods to determine the significance and power of study. Results : In this study statistically significant correlation was not found between age and CAIMT (p=0.3690). Significant increase in carotid artery intima media thickness was found in patients having microalbuminuria. Among microalbuminuric patients 35 patients (74.5%) having CAIMT ≥1mm & 15(28.3%) patients having CAIMT ≤1mm.Among normoalbuminuric pts only 12 pts(25.5%) having CAIMT ≥1mm.The value of Pearson’s correlation coefficient was r=0.4245, which is significant (p<0.05). It was found that statistically significant aassociation was found between HbA1C & CAIMT (P=0.0424). Conclusion: Carotid artery intima media thickness evaluated by the high resolution ultrasonography reflects an early index of cardiovascular disease. The present study reveals statistically significant correlation is found between Microalbuminuria & Carotid artery intima media thickness (p<0.0001). Routine screening of carotid artery IMT by B-mode USG in type 2 diabetic patients with microalbuminuria is necessary. It helps us not only to detect early atherosclerosis but to prevent further development of diabetic nephropathy and cardiovascular events by applying more intensive therapy.
Authors and Affiliations
Dr Avijit Saha
Keywords
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