A Study on Efficacy of Prophylactic Tranexamic Acid in Reducing Blood Loss during Elective Lscs
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Background: Obstetric haemorrhage accounts for 20 – 25% of maternal mortality and morbidity. Anti fibrinolytics are being widely used in various surgeries for reducing blood loss. Objective: The objective was to determine the role of prophylactic tranexamic acid in reducing blood loss during elective lscs. Study Design: A randomized case control study Place of Study: Chengalpattu medical college and hospital Methodology: A randomized case control prospective study was conducted in 100 women undergoing elective lscs between june 2017 to november2017. Among the 100 women undergoing lscs 50 were randomized to study group and the other 50 to control group. Study group patients received 1gm of tranexamic acid in 100ml normal saline 15mins prior to surgery while the control group patients received the usual preoperative care. Amount of blood loss , duration of surgery , the use of additional uterotonics and preoperative hemoglobin and postoperative hemoglobin were calculated in both groups. Results: The amount of blood loss was significantly lower in study group (406.96 ± 58.11) when compared to control group (460.1 ± 70.15). The duration of surgery was lower in study group (33.10 ± 5.33) when compared to control group(42.10 ± 3.65). Also the 24hrs postoperative hemoglobin was significantly higher in study group (11.83 ± 1.1) compared to control group(10.34 ± 1.03). Conclusion: Tranexamic acid significantly reduces the blood loss during lscs. It was not associated with any side effects or complications.
Authors and Affiliations
Prof. Dr. S. Sampathkumari M. D Og, Dr. Arulmozhi M. S Og, Dr. Ranjini Priya M. S Og, Dr. Mahalakshmi. V M. S Og
Keywords
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- EP ID EP362442
- DOI 10.9790/0853-1702075963
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