A STUDY ON EYELID AND CONJUNCTIVAL NEOPLASM IN A TERTIARY CARE CENTRE IN EASTERN INDIA
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 74
Abstract
BACKGROUND Eyelid and conjunctival tumours (benign and malignant) are very common in a tropical country like India causing not only cosmetic deformity, but also endangering patients’ life. The aim of our study is to determine the sociodemographic factors and clinicopathological assessment in order to early diagnosis and treatment. MATERIALS AND METHODS The present study is an observational study involving the cases with primary eyelid and/or conjunctival tumours. After thorough clinical history including detailed demographic details and clinical examination, the cases are admitted in the hospital. After undergoing thorough preoperative evaluation, FNAB or partial excision biopsy or total excision biopsy of the tumour mass is done by single competent ophthalmic surgeon and sent for histopathological analysis. The cases were classified into two major groups, eyelid neoplasm group and conjunctival neoplasm group. Each major group was subdivided into benign neoplasm and malignant neoplasm groups. The demographic details, clinical history, examination findings and results of the histopathological analysis is documented, appropriately tabulated and reported and statistical calculations done. RESULTS In this prospective observational study, 133 eyes of 133 patients (M:F=70:63) with primary eyelid and conjunctival tumour attending OPD and oculoplasty clinic at Regional Institute of Ophthalmology, Kolkata, were recruited into the study. There were a total of 103 (77.44%) eyelid neoplasms and 30 (22.55%) patients were having conjunctival neoplasms. Out of the 103 eyelids, neoplasms diagnosed 42.72% (n=44) of them were histopathologically diagnosed as benign and 57.28% (n=59) as malignant. Of the 59 cases diagnosed as malignant, four most common eyelid malignant neoplasms were sebaceous cell carcinoma (n=22, 37%), basal cell carcinoma (n=15, 25%), squamous cell carcinoma (n=10, 17%) and malignant melanoma (n=7, 12%). Among the 30 conjunctival neoplasms histopathologically diagnosed, the majority of them were benign (n=19, 63.33%). The rest being made up of malignant (n=7, 23.33%) and premalignant (n=4, 13.33%). CONCLUSION The most common benign lesion of the eyelid was a chalazion and most common benign lesion of the conjunctiva was melanosis. Basal Cell Carcinoma (BCC), though malignant, has a good prognosis if removed completely. The relative frequencies of squamous cell carcinoma in various studies showed that there was a wide variation. Although, it has been noted that this cancer is seen less frequently in individuals with dark skin, it is interesting to note that the proportion of squamous cell carcinoma was relatively high in this study conducted in India. The results in this study provide further evidence in favour of a higher proportion of sebaceous cell carcinoma in India. The conjunctival malignant neoplasms were dominated by squamous cell carcinoma, which was again in accordance with previous studies in Asian populations.
Authors and Affiliations
Soumya Swarup Chattopadhyay, Soumyadeep Majumdar, Raghuraj S. Hegde
Keywords
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- EP ID EP283455
- DOI 10.18410/jebmh/2017/874
- Views 73
- Downloads 0
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