A Study on Growth Parameters and Clinical Profile in Children with Thalassemia Major
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 2
Abstract
Objectives: To study the growth parameters & clinical & demographic profile in pediatric patients living with thalassemia majorMethods: This cross-sectional, descriptive and analytical study was carried out on 30 thalassemic patients who received blood transfusion therapy at Kharagpur SD Hospital with respect to growth parameters such as Height/Length, Weight, Head Circumference; demographic profile such as age, gender & clinical profile such as presenting complaint & blood groups were studied. Collected data was compared to existing standardized IAP & WHO growth chart. Results: Age distribution in our study group was bimodal (4 to 6 yrs& 9-12 yrs) with a male female ratio of 1:1, B positive blood group being the most common blood group. Most common presenting complaint was generalized weakness with mean hemoglobin of 4.33 + 0.4 at presentation. Weight for age, height for age both were significantly low when compared to the standard growth curves with relative sparing of head growth (head circumference) with trend lines showing decline in Height & weight for age with age. A very high prevalence of both underweight (70%) and stunting (67%) noted in our study group, with almost 90% had a height for age & weight for age below mean. Conclusions: Thalassemia major patients, are highly prone to growth failure with high prevalence of stunting and wasting which aggravates with age with relative sparing of head implying the need for effective early childhood interventions, growth monitoring, properly timed regular blood transfusion, sensitizing patients' family regarding early recognition of anemia, elevating the average pre transfusion Hemoglobin level (Hb) is the key to combat this severe growth faltering.
Authors and Affiliations
ParthaSarathi Das, Saikat Majumdar
Keywords
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