A STUDY ON LIPD PROFILE IN PROSTATE CARCINOMA PATIENTS ADMITTED IN AIIMS, NEW DELHI.
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2014, Vol 3, Issue 1
Abstract
Prostatic carcinoma is a leading cause of morbidity and mortality in elderly men. Hyper cholesteremia has been classically associated with increased risk of prostate cancer. Recent studies have also shown hypocholesteremic patients raising doubts as whether cholesterol helps in initiating tumour or just consumed more by the tumor cells. These studies have developed a growing consensus whether cholesterol has any role in cell proliferation and tumorogenesis. The present study aims to explore this event. Serum levels of lipids and prostate specific antigen (PSA) were measured in carcinoma prostate, benign prostatic hyperplasia, sham controls (radical cystectomy patients) and normal subjects using enzyme based kit methods. Plasma LDL cholesterol was decreased in carcinogenic specimen(s) as compared to the specimen(s) from normal subjects.
Authors and Affiliations
Govind Singh| Assistant professor, Department of Biochemistry, Government Medical College, Haldwani Distt- Nainital, Uttarakhand (India), Shrimanjunath Sankanagoudar| Senior resident, Department of Biochemistry, All India Institute of Medical Sciences, Ansari Nagar, New Delhi - 110029, India., Prem Nath Dogra| Professor and head, Department of Urology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi - 110029, India., Sandeep R. Mathur| Associate professor, Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi - 110029, India., Nimai C. Chandra*| Associate professor, Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi - 110029, India.
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