A STUDY ON ORAL GLUCOSE TOLERANCE TEST IN CIRRHOSIS
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 62
Abstract
BACKGROUND Overt diabetes mellitus (diabetes mellitus) and impaired glucose tolerance test has been reported 21%-30% and 60-80% respectively in patients with liver cirrhosis.1 The aim of the study is to assess the prevalence of impaired glucose tolerance among cirrhosis patients with normal blood sugar and to improve their long-term survival by early detection of impaired glucose tolerance by OGTT and timely institution of treatment. MATERIALS AND METHODS This study was conducted among 100 cirrhosis patients attending Gastro Clinic at Government Rajaji Hospital, Madurai. Patients with overt diabetes, complication of cirrhosis such as bleeding manifestation, hepatic encephalopathy, spontaneous bacterial peritonitis and moderate-to-severe ascites were excluded from the study. RESULTS In our study, the frequency of glucose metabolism disorder was 64%, of which 46% were IGT and 18% were diabetes mellitus. Such a high incidence of latent glucose metabolism disorder in cirrhosis was revealed with the routine use of OGTT. This test should be recommended routinely for cirrhosis patients for early detection of glucose metabolism disorder. CONCLUSION In our study, the frequency of glucose metabolism disorder was 64% among 46% were IGT and 18% were diabetes mellitus. This 64% was revealed after OGTT, which indicates of high incidence of latent glucose metabolism disorder in cirrhosis.
Authors and Affiliations
Hayatkhan Sikkandar Basha, Chelliah Dharmaraj
Keywords
Related Articles
- EP ID EP228282
- DOI 10.18410/jebmh/2017/743
- Views 69
- Downloads 0
PRIMARY GLAUCOMAS- SCREENING, EVALUATION AND MANAGEMENT IN A TERTIARY CARE HOSPITAL, CENTRAL INDIA
BACKGROUND Early detection and management of glaucoma can reduce the visual morbidity. As the population-based screening programs were not cost effective because of low prevalence of glaucoma in general population, this...
A CASE SERIES ON FISH BILE TOXICITY
A case series of 3 cases of fish bile poisoning are reported. After ingestion of gall bladder of Labeo rohita for alleged vision improvement, generally presented with gastrointestinal symptoms such as cramping pain abdom...
CHORANGIOSIS PLACENTA
Chorangiosis is an uncommon, miscellaneous vascular pathology of terminal chorionic villi demonstrating proliferation of villous capillaries without stromal hypercellularity.1, 2 Studies show high perinatal mortality and...
A COMPARATIVE CLINICAL EVALUATION OF ORAL CLONIDINE VS. PREGABALIN PREMEDICATION FOR ATTENUATION OF HAEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND INTUBATION- A PROSPECTIVE RANDOMISED DOUBLE BLINDED PLACEBOCONTROLLED STUDY
BACKGROUND Endotracheal intubation is considered gold standard in patients undergoing general anaesthesia. Direct laryngoscopy and tracheal intubation result in an increase in blood pressure and heart rate, the so called...
PREVALENCE OF HEPATITIS C VIRUS INFECTION IN NON INSULIN DEPENDENT DIABETIC PATIENTS (NIDDM)
The present study was done to evaluate the prevalence of hepatitis C virus (HCV) infection in non-insulin dependent diabetic patients (NIDDM) and to investigate influence of HCV seropositivity on several factors such as...