A STUDY ON PLATELET COUNT AND INDICES IN ACUTE CORONARY SYNDROME
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 28
Abstract
BACKGROUND Acute coronary syndrome is a set of signs and symptoms due to rupture of a plaque and is a consequence of platelet rich coronary thrombus formation. Platelet parameters, especially MPV could be an important and reliable marker in early detection of acute coronary syndrome when other markers are not available. Aim- To study the effect of platelet count and their indices, platelet volume and platelet distribution width and their prognostic significance in acute coronary syndrome. MATERIALS AND METHODS This was a case control study, and sample size was taken for convenience. Patients admitted to Rajiv Gandhi Government General Hospital, Madras Medical College, Chennai during the period extending from April 2016 to September 2016, were included in the study for convenience sake. A total of 100 patients were included in the study, in which 50 patients were cases admitted with chest pain and diagnosed as ACS. The control group considered of 50 age matched subjects who were admitted for chest pain evaluation and subsequently found to be non-cardiac chest pain after performing relevant investigations. Blood samples were taken at the time of admission for platelet parameters. RESULTS A total of 50 patients with acute myocardial infarction and 50 age matched controls were studied. The mean platelet count of the cases was 4.98±0.23 lakhs/mm³ and that of controls was 1.29±0.42 lakhs/mm³. Mean Platelet Volume (MPV) was significantly elevated in acute myocardial infarction (10.2±1.1 femtolitres) when compared with controls (8.29±0.9 femtolitres). CONCLUSION Platelet parameters mainly MPV and PDW are readily available and relatively simple and inexpensive laboratory tests, which were detected to be significantly raised in patients who have suffered an acute coronary syndrome.
Authors and Affiliations
Anitha Moorthy, Sundaramurthy Ganesan, Karthigeyan Thanjavur Sethuraman, Ramesh Bhaskaran
Keywords
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- EP ID EP537780
- DOI 10.14260/jemds/2018/718
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