A study to compare the effects of single dose intravenous dexmedetomidine and clonidine on bupivacaine spinal anaesthesia
Journal Title: Medpulse International Journal of Anesthesiology - Year 2019, Vol 9, Issue 1
Abstract
Background: Dexmedetomidine, also an α2-adrenergic agonist, used for pre-medication and as additive to general anesthesia. Dexmedetomidine when given intravenously decreases the inhalational anesthetic and opioid requirements during general anesthesia. This study has been undertaken as the hypothesis that dexmedetomidine and clonidine when given intravenously might prolong the duration of spinal analgesia. This technique may be helpful for increasing the duration of spinal anesthesia. Aim and objective: The aim of this study is to evaluate the effects of intravenous dexmedetomidine and clonidine on duration of spinal anesthesia and to assess the hemodynamic changes and the level of sedation. Materials and methods: It is a prospective Randomised study conducted at Government Rajaji hospital Madurai. A total of 90 patients were randomly allotted into three groups of 30 each. Group A received dexmedetomidine through intravenous route and Group B received clonidine through intravenous route and Group C received normal saline through intravenous route. Results: The average time taken for onset of sensory block is 57 seconds for dexmedetomidine group ,74 seconds for clonidine group and 93 seconds for control group. Thus dexmeditomidine has faster onset of sensory blockade. Mean duration time for two segmental regression in groupA is prolonged and was statistically significant than group B and group C. Conclusions: From our study it is concluded that dexmedetomidne can be safely used as preoperative sedation to hasten the onset of subarachnoid block and to prolong the sensory blockade without side effects.
Authors and Affiliations
P Ramadevi, T Nirmaladevi
Keywords
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- EP ID EP520884
- DOI 10.26611/10159112
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