A study to evaluate acute pancreatitis using modified CT severity index and correlating with clinical outcome in tertiary care hospital
Journal Title: Medpulse International Journal of Radiology - Year 2019, Vol 9, Issue 2
Abstract
Objectives: This study was conducted to assess the prognostic value of MDCT in patients with acute pancreatitis and to correlate the CT Severity Indexes with clinical outcome. Material and Methods: 60 patients diagnosed with acute pancreatitis who underwent contrast- enhanced MDCT within 3 days of the onset of symptoms during the study period were included in the study. The severity of the pancreatitis was scored using both the modified CT severity indexes and CT severity indexes. Patient clinical outcome was scored using parameters such as: mean duration of hospital stay, the need for surgical intervention, occurrences of infection, end organ failure and death. For both the CT and modified CT severity indexes, correlation between the severity of the pancreatitis and patient outcome was estimated using the percentage, frequency charts and chi-square test. Results: When applying the modified index, the severity of pancreatitis and the following parameters significantly correlated than the CT severity index: the length of the hospital stay (2-23 days), the occurrence of end organ failure (28/60 patients) (modified CT severity index [p = < 0.001] vs CT severity index [p = 0.035]). Highly significant correlation between the grading of severity of pancreatitis and the prediction of systemic infection (21/60 patients) was seen using the modified CT severity index (p = 0.001), not the CT severity index (p = 0.172). There was no significant correlation between grading of severity of pancreatitis based on the modified CT severity index and the need for the surgical intervention (modified index [p = 0.117] vs CT severity index [p = 0.017]). Conclusion: There was highly significant correlation between the MCTSI score and the prediction of end organ failure, systemic infection and duration of hospital stay than CTSI score. MCTSI is a very useful tool for the screening of patients with acute pancreatitis for the classification of severity accurately and to predict the clinical outcome when used before three days of symptom onset.
Authors and Affiliations
Rahul J Shirol, Venkatesh Karanth
Keywords
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- EP ID EP539508
- DOI 10.26611/1013929
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