A Study to Observe Blood Loss Reduction by Tranexamic Acid Before and After Caesarean Section
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 5
Abstract
Introduction: Tranexamic acid ,an antifibrinolytic is said to be beneficial in reducing blood loss during caesarean section. Aim: To assess the role of tranexamic acid in controlling blood loss during caesarean section. Materials and methods: This study was conducted to clinically observe the blood loss reduced by tranexamic acid during and after caesarean section.300 patients were selected for the study, 150 as study group and 150 as Control group. Results: Age incidence-44.3% of the cases belong to the age group 25-29 years.57% of the cases were primigravida and 29% of the cases were 2nd gravida.93% of the cases were emergency cases and 7% of the cases were elective cases. There was no statistically significant difference in the subjective characters in between the two groups. Conclusions: Tranexamic acid significantly reduced the blood loss from placental delivery to 2 hour post partum.There was statistically significant fall in blood pressure and rise in PR and significant change in RR in the control group compared to the study group. Hb level was significantly reduced in the control group compared to the study group postoperatively but without significant increase in the need for blood transfusion. Incidence of vomiting was higher in the study group and wound infection was higher in the control group but without statistical significance. This vomiting may be drug related and wound infection may be related to blood collection in the wound. None of the patients in both the groups had thromboembolic complications postoperatively. Neonatal outcome was similar in both the groups.
Authors and Affiliations
M. Mumtaj
Keywords
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