Acute Erythroblastic Leukemia Revealed by Dermatological Manifestations
Journal Title: Open Access Journal of Oncology and Medicine - Year 2018, Vol 1, Issue 2
Abstract
Acute erythroblastic leukemia is characterized by the proliferation of a predominant erythrocyte population on other lineages. Cutaneous manifestations remain rare and misleading, making the diagnosis of difficult to suspect as first-line. Here, we report an unusual and rare case of acute leukemia in a 24 year old male with gingival hypertrophy and dermatological manifestations. This case emphasizes that dentist and dermatologist should be well acquainted with these manifestations of systemic diseases. We report the case of 24 years old patient, with no significant pathological history, who had a rash for 10 days in a context of fever and very bad general condition. At admission the patient was febrile, tachycardic and dyspneic. Physical examination revealed erythemato-purplished papulo-nodules on the face, trunk, limbs and a gingival hyperplasia. The oral state was deplorable. Bilateral cervical lymphadenopathy was also found without the patosplenomegaly (Figures 1-3). The biological assessment showed a CRP of 150 and a pancytopenia with a Hbat 7.5g / dl, normal VGM and CCMH, a deep thrombocytopeniaat 85000 / l, leukocytesat 1500 / l. The blood smear showed 35% of circulating blasts and 22% of erythroblasts.
Authors and Affiliations
Moustaide K, Nassiri A, Gallouj S, Mernissi FZ
Keywords
Related Articles
- EP ID EP583041
- DOI 10.32474/OAJOM.2018.01.000106
- Views 82
- Downloads 0
Metformin Treatment Represses Vascular Endothelial Growth Factor Gene Transcription in MCF-7 Breast Cancer Cells
Background/Aim:Targeting angiogenesis preferentially in cancer is a promising approach to improve treatment efficacy and safety. The aim of this study is investigate potential upregulation of Krüppel like factor-4(KLF-4)...
Aspirin, Vascular Disease and Cancer: 50 Years of Controversy and the Jury’s Still Out!
The story of aspirin and vascular disease starts with John O Brien, a haematologist in Portsmouth in the 1960s, who reported that the ingestion of 150mg of aspirin substantially reduced the aggregation of platelets [1]....
Librarians who Request for Reprints Including those in Oncology
A 13-year retrospective study of reprint requestors was undertaken with special reference to those from research libraries. It was found that 2.8 percent of the total 2,053 requests were from such librarians. They prepon...
Cancer and Advantages of Immunosuppression
As oncologists learn to target the immune response to “self and non-self,” a delicate therapy balance will eventually be achieved with predictable outcomes, benefits, and toxicity in the fightThe study of how the immune...
Metastatic Hormone and Her-2 Positive Breast Cancer: A Community Approach
Metastatic hormone-receptor and HER-2 positive (triple-positive) breast cancer provides a treatment dilemma for clinicians. The current guidelines offer a variety of options in the first and second line for metastatic br...