Acute invasive rhinosinusitis case caused by Aspergillus flavus in two patients prediagnosed with mucormycosis
Journal Title: Journal of Microbiology and Infectious Diseases - Year 2015, Vol 5, Issue 3
Abstract
Acute invasive rhinosinusitis caused by Aspergillus spp. may lead to invasive disease and mortality, especially in immunocompromised individuals. In this report, two invasive fungal rhinosinusitis cases in an immune compromised patient have been presented that were pre-diagnosed with mucormycosis, but with a positive culture for Aspergillus flavus. Twenty-four years old male patient with aplastic anemia and seven years old patient with acute lymphoblastic leukemia; facial pain, edema, and necrotic lesions developed in both cases. Tissue samples were obtained from lesions through the nose by biopsy for definitive diagnosis. Septate fungal hyphae observed on the microscopic examination of the specimen, and A. flavus was isolated in the culture in both cases. Surgical debridement could not be performed because of patients’ general conditions. Despite antifungal therapy and treatments, patients died. Delay in diagnosis and treatment may lead to high mortality rates. These cases emphasize the importance of diagnosis with culture. J Microbiol Infect Dis 2015;5(3): 137-141 Key words: Acute invasive fungal rhinosinusitis, Aspergillus flavus, diagnosis
Authors and Affiliations
Müge Aslan , Yasemin Öz, Özcan Bor, Eren Gündüz , Filiz Akşit
Keywords
Related Articles
- EP ID EP106443
- DOI 10.5799/ahinjs.02.2015.03.0193
- Views 152
- Downloads 0
Three cases of necrotising fasciitis caused by Pseudomonas aeruginosa and Stenotrophomonas maltophilia: the importance of immunosuppression
Necrotizing Fasciitis (NF) is a life-threatening infectious emergency, characterized by rapidly progressive fascia and sub-cutaneous tissue necrosis. NF carries a high mortality rate in the neutropenic period of immunos...
Streptococcus pneumoniae acquisition among vaccinated Malaysian Hajj Pilgrims and its associated factors
Objective: To describe the acquisition of Streptococcus pneumoniae among Malaysian hajj pilgrims and to determine the association with pneumococcal vaccination and respiratory symptoms. Methods: This was a cross section...
Ewingella americana ’ya bağlı gelişen ventilator ilişkili pnömoni olgusu: Türkiye’den ilk vaka
Ewingella americana özellikle immunsuprese hastalarda ciddi enfeksiyonların çok ender bir sebebidir. Biz bu çalışmada bir yoğun bakım hastasında seftriaksonla başarı ile tedavi edilen bir ventilator ilişkili pnömoni olgu...
Susceptibility of Minocycline against Carbapenem Resistant Gram-Negative Bacilli
Susceptibility of Minocycline against Carbapenem Resistant Gram-Negative Bacilli Anup R Warrier1; Rachana Babu2 1Department of Infectious Diseases, Aster Medcity, Kochi, Kerela, India 2Department of Microbiology, Aster M...
A nosocomial outbreak of Crimean-Congo hemorrhagic fever
Objectives: An outbreak of nosocomial Crimean-Congo Hemorrhagic Fever (CCHF) occurred in a university hospital in May 2014. The index case was hospitalized with a preliminary diagnosis of intoxication, liver failure and...