ACUTE ORAL TOXICITY OF MUCUNA PRURIENS IN SWISS ALBINO MICE
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 5
Abstract
Mucuna pruriens, belonging to the botanical family Fabaceae, has been used in traditional Ayurvedic Indian medicine for various ailments including Parkinson’s disease. The current study reports the outcome of acute oral toxicity investigation of ethanolic extract of M. pruriens (whole plant) on Swiss albino mice. No mortalities or evidence of adverse effects have been observed in Swiss albino mice following acute oral administration of ethanolic extract of M. pruriens at the dose of 2000 mg/ kg. This is the first report on the acute oral toxicity of M. pruriens and thus the findings of this study provide scientific validation on the use of the M. pruriens as a medicine for treating various ailments.
Authors and Affiliations
Sushant Parekar , Arju Somkuwar
Keywords
Related Articles
- EP ID EP103256
- DOI -
- Views 111
- Downloads 0
MOLECULAR ALTERATIONS AND TARGETED THERAPY IN OESOPHAGEAL SQUAMOUS CELL CARCINOMA
Oesophageal cancer is one of the most fatal cancers. Oesophageal squamous cell carcinoma is the predominant histological subtype worldwide with a high incidence rate in Asia. Although significant advancement has been mad...
FORMULATION DEVELOPMENT AND EVALUATION OF MOUTH DISSOLVING TABLET OF BAMBUTEROL HYDROCHLORIDE
The aim of the present study was to prepare mouth dissolving tablets of Bambuterol hydrochloride by using pertinent disintegrants. The tablets were prepared using mannitol and lactose along with two levels of disintegran...
QUALITATIVE EVALUATION OF MARKETED AYURVEDIC RED TOOTH POWDER BY NAMBURI PHASED SPOT TEST
Simple and precise quality control analysis of consumer goods is the goal of rising FMCG sector. Ayurvedic red tooth powders are one of the most popular FMCG products in today’s market. The main ingredient (≥80%) of thes...
CHARACTERIZATION OF PAPAYA FRUIT MEDIATED SILVER NANOPARTICLES AND EVALUATION OF ITS ANTIMICROBIAL AND WOUND HEALING ACTIVITY
The field of Nanotechnology is the most active area of research in modern material science. Though there are many chemical as well as physical methods, green synthesis of nanomaterial is the most emerging method of synth...
TEMPERAMENTAL ANALYSIS IN CASE OF MENORRHAGIA IN REPRODUCTIVE AGE GROUP
The term menorrhagia is derived from Greek (men=month rhegia=to brust forth). Menorrhagia denotes cyclic regular bleeding which occur excessive in amount or duration or both. Menorrhagia means excessively heavy menstruat...