Acute pancreatitis and recurrent acute pancreatitis: an exploration of clinical and etiologic factors and outcomes
Journal Title: Jornal de Pediatria - Year 2019, Vol 95, Issue 6
Abstract
Objective To describe the epidemiology and clinical features of acute pancreatitis and recurrent acute pancreatitis in children. Methods Observational and retrospective study with an analytical component. Patients were classified into two groups: Acute pancreatitis and recurrent pancreatitis. The relationship with each parameter obtained was analyzed using the chi-squared test, Student's t-test, or the Mann–Whitney U test. Results There were 130 patients with acute pancreatitis; recurrent pancreatitis was diagnosed in 23.8% of the cases. The most frequent causes were anatomical (29.6%), pharmacological (19.2%), and biliary (14.6%), although in 29.2% etiology was not identified. Fasting lasted 3.5±3.8 days and parenteral nutrition was indicated in 26.9% of the cases for 10.8±11.3 days. A statistical association with anatomical (p=0.02) and pharmacological causes (p=0.01) was found in the recurrent pancreatitis group; no other differences between acute pancreatitis and recurrent pancreatitis groups were observed. The mortality rate was 3.1%, it was not attributable to acute pancreatitis in any cases. Conclusion Acute pancreatitis is associated with a high frequency of acute recurrent pancreatitis. Severity and complications did not show statistically significant differences in this investigation. Anatomical etiologies were the most relevant cause in this cohort. Fasting time and parenteral nutrition use were relevant. Genetics testing is required in this population.
Authors and Affiliations
Eileen Sepúlveda
Keywords
Related Articles
- EP ID EP664351
- DOI 10.1016/j.jped.2018.06.011
- Views 93
- Downloads 0
Quality of human milk expressed in a human milk bank and at home
Objective To evaluate the quality of the human milk expressed at home and at a human milk bank. Methods This a retrospective, analytical, and observational study, performed by assessing titratable acidity records and th...
Costs of hospitalization in preterm infants: impact of antenatal steroid therapy
Objective To estimate the costs of hospitalization in premature infants exposed or not to antenatal corticosteroids (ACS). Method Retrospective cohort analysis of premature infants with gestational age of 26–32 weeks wi...
Mother and child characteristics at birth and early age leukemia: a case-cohort population-based study
Objective The population-based cancer registries (PBCR) and the Information System on Live Births in Brazil (Sistema de Informações sobre Nascidos Vivos [SINASC]) have information that enables the test for risk factors a...
Curricular intervention increases adolescents’ knowledge about asthma: a randomized trial
Objectives To evaluate the impact of a curricular intervention concerning the knowledge about asthma among adolescents from a public school. Methods This was a randomized, controlled trial study on a curricular interven...
Is a lack of sleep harming adolescents’ academic prospects in the digital age?
Adolescence is a crucial developmental period for defining one's academic expectations. In many countries, teenagers must prepare for and take national exams. Those outcomes may have a long-lasting impact on the future c...