ADDITIONAL VALUE OF POST-THERAPY 131I SPECT/CT IN PATIENTS WITH DIFFERENTIATED THYROID CANCER
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 19
Abstract
BACKGROUND Generally, it is seen that SPECT/CT images are more useful than the planar images. We compared post-therapy 131I imaging findings on planar and SPECT/CT scans to assess the clinical utility of SPECT/CT in management of patients with differentiated thyroid cancer. MATERIALS AND METHODS Post-therapy imaging was performed at 4-7 (when 5mR/hrs. exposure rate were observed by the survey meter) days after 131I administration and all patients underwent whole-body scintigraphy and SPECT/CT scanning on the same day. A generalised McNemar1 was used to determine to establish the agreement between planar whole-body imaging and SPECT/CT for the assignment of benign, equivocal and malignant findings. RESULTS In 44 patients, 32 of the 44 patients underwent postsurgical 131I ablation of residual thyroid tissue and 12 of 44 patients, 2 patients were treated twice. Hence, a total of 46 scans were analysed. SPECT/CT helped to localise focal iodine uptake and characterise it as either normal or abnormal thereby reducing the need for additional imaging studies. In post-thyroidectomy patients, SPECT/CT findings affected the ATA risk classification with implications for management by changing the interval for clinical followup and the need for additional imaging and laboratory tests. Our study found an 11% change in nodal status in the postsurgical group. Change in patient management was observed in 18%. CONCLUSION SPECT/CT enabled more accurate characterisation of focal iodine accumulation in patients.
Authors and Affiliations
Satyawati Deswal, Dhananjay Kumar Singh, Vibhor Mahendru, Kavindra Pratap Singh
Keywords
Related Articles
- EP ID EP215056
- DOI 10.18410/jebmh/2017/208
- Views 87
- Downloads 0
THE ILL EFFECTS IN THE ORAL HEALTH AMONG THE ADULTS DUE TO THE CONSUMPTION OF AERATED DRINKS
BACKGROUND Excessive consumption of carbonated soft drink is detrimental to oral and general health and the popularity of the aerated drinks among adults has grown exponentially. This study aims at determining the preval...
A STUDY ON MORPHOMETRIC CHANGES OF THE SUPRARENAL GLAND AT VARIOUS STAGES OF DEVELOPMENT
BACKGROUND The suprarenal glands are located just above the kidneys from their position the name is derived. They have no other relation to the kidneys, either functionally or developmentally. Their development is taken...
OUTCOMES OF LIFT VERSUS SETON IN COMPLEX FISTULA-IN-ANO- A COMPARATIVE STUDY
BACKGROUND A fistula-in-ano is an abnormal tract or cavity establishing a communication between rectum or anal canal and the perianal area. Surgery is the treatment of choice with the goals of draining infection, eradica...
EFFECTIVENESS OF MINIMALLY INVASIVE OESOPHAGECTOMY IN REDUCING MORBIDITY FOR CANCER OESOPHAGUS
BACKGROUND Surgery remains the gold standard treatment modality for oesophageal carcinoma especially for middle third and lower third segments of oesophagus. Open trans-hiatal or transthoracic oesophagectomy is associate...
A PROSPECTIVE OBSERVATIONAL STUDY OF THE CLINICOPATHOLOGICAL PROFILE, EPIDEMIOLOGICAL RISK FACTORS AND FALLOPIAN TUBE MUCOSAL INVOLVEMENT IN OVARIAN CANCER
BACKGROUND Many of the ovarian tumours traditionally thought to be of ovarian origin is now thought to primarily originate in other pelvic organs and ovarian involvement is actually secondary. MATERIALS AND METHODS A pro...