Administration of Drug Induce Liver Injury to the Inpatients with Liver Disease

Journal Title: Indonesian Journal of Clinical Pharmacy - Year 2012, Vol 1, Issue 2

Abstract

Drug induced liver injury is a serious human health problems. Pre-existing liver diseases are risk factor of liver injury by the drugs. The study was conducted to evaluate the use of drug induced liver injury in patients hospitalized with liver disease at one hospital in Kota Tasikmalaya. Informations were collected retrospectively in the period 2010-2011 from the patient’s medical record. A total of 52 patients research subjects were discovered 50 patients (96%) using drug induced liver injury and 2 patients (4%) did not use it. Drug induced liver injury most widely used were ranitidine (31.3%), ceftriaxone (23.1%), and paracetamol (16.4%). Level of the DILI usage in patient with liver disease was relative high (96%). Further research is needed to determine the effect of the drug induced liver injury to liver injury.

Authors and Affiliations

Sindy E. Cinthya, Ivan S. Pradipta, Rizky Abdulah

Keywords

Related Articles

Validity and Reliability of EORTC QLQ C-30 Questionnaire in Assessing Quality of Life of Gynecological Cancer Patients in Sanglah Hospital Denpasar

The impacts of cancer and its treatment can be measured by indicators of quality of life using the EORTC QLQ C-30 questionnaire. A cross-sectional study was done on 30 patients in Sanglah Hospital Denpasar. Data were col...

The Correlation of Age Factor, Administration, and Metformin Dose Against Risk of Side Effect on Type 2 Diabetes Mellitus

Metformin is an antidiabetic oral medicine commonly recommended as first line treatment on type 2 diabetes mellitus. Metformin can caused drug related problems (DRPs) such as gastrointestinal disorders, e.g. diarrhea, na...

The Effect of Blood Pressure Feedback Intervention to Doctors on the Change of the Hypertensive Patient Therapy Cost

An analytical intervention study has been done with the aim to evaluate the therapy cost-effectiveness among the hypertensive ambulatory patients at four hospitals in Yogyakarta city. The study was done with the scatter-...

The Renal Toxicity of Welding Fumes in Heavy Equipment Manufacturer Workers

Exposure to welding fumes in the workplace has been associated with decreasing renal function. We studied renal function parameters in men workers from heavy equipment manufacturer exposed to welding fumes. This study ai...

N-MID Osteocalcin (N-MID Oc) and β-Crosslaps (β-CTx) as Biochemical Markers of Bone Turnover in Menopausal Women

Osteocalcin is a marker compound for bone formation while the β-crosslaps a fragment split from collagen type 1. The aims of this study were to determined of the value of N-MID osteocalcin (N-MID Oc) and β-CTx as a bio...

Download PDF file
  • EP ID EP333668
  • DOI -
  • Views 125
  • Downloads 0

How To Cite

Sindy E. Cinthya, Ivan S. Pradipta, Rizky Abdulah (2012). Administration of Drug Induce Liver Injury to the Inpatients with Liver Disease. Indonesian Journal of Clinical Pharmacy, 1(2), 43-48. https://europub.co.uk./articles/-A-333668