Adult Type Chronic Myeloid Leukemia in Children: A Case Report
Journal Title: Saudi Journal of Medicine - Year 2018, Vol 3, Issue 11
Abstract
Chronic myeloid leukemia is a malignant clonal expansion of hemato¬poietic progenitor cells causally linked to a specific chromosomal abnormality, the Philadelphia chromosome. It occurs uncommonly in childhood, accounting for only 2 to 5% of all pediatric leukaemias with an annual incidence of about 1 per million in this age range. We describe one such case of chronic myeloid leukemia in an 11 year old boy, who presented with massive splenomegaly and hyperleukocytosis. The diagnosis was made from peripheral blood smear examination, supported by karyotypic study. Because of the infrequency of its occurrence, it was thought of interest to report this case of CML and to review certain interesting features of this entity in the pediatric population.
Authors and Affiliations
Hendi Rajae, Tlamçani Imane, Mahha Mariam, Tadmori Ilham, Benmiloud Sara, Hida Moustapha, Amrani Hassani Moncef
Keywords
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