Advancement and Future Perspectives of Prostate Cancer Treatment by Using Plant Bio-actives: A Review
Journal Title: Journal of Chemistry and Environment - Year 2022, Vol 1, Issue 1
Abstract
Prostate cancer (PCa) is the world's second most lethal and hateful disease in people. Even while chemotherapy medications have made considerable progress against cancer disease, the body still has to deal with their toxic side effects. In order to produce anticancer medicines with the lowest cost and treatment time, mostly people are using mechanistic techniques. In addition to chemotherapy advanced treatment techniques are also used in clinical practices, and they have an excellent healing results by enhancing patient survival rates. The social care net faces serious challenges because of the lack and high cost of modern therapeutic techniques. The side effects of chemotherapeutic drugs and expensive advance techniques triggered the patient interest towards phytochemicals drugs which indicate that nature always attracts human to fulfill their medical needs at very low cost. The pharmaceutical industries are showing strong interest in recent research, which has led to the addition of a quite large number of phyto-medicines in PCa therapeutic practices. Currently, several experimental epidemiological and clinical research reports confirmed that plant bio-actives play a significant role in PCa prevention by using different mechanistic ways such as suppressing adhesion, anti-angiogenesis, pro-apoptosis, anti-proliferation, invasion and migration. This review systematically highlighted various strategies to treat PCa and advances in research by using different bioactive plant extracts and isolated components that have been tested for PCa therapy along with corresponding clinical and epidemiological studies.
Authors and Affiliations
Hira Zulfiqar, Hunain Zulfiqar, Muhammad Furqan Farooq, Iqbal Ahmed, Iqra Rani, Farman Ullah
Determination of Antioxidant Activity of Acacia Nilotica Linn from different Regions of Baluchistan (Pakistan)
Free radicals are naturally occurring species with unpaired electrons that are formed during normal metabolic processes. Their formation in a high amount may cause oxidation of essential structural molecules of cell, the...
Seasonal Variation of Fe, Mn, and Pb in Groundwater of Northwestern Bangladesh
Groundwater is one of the most significant natural resources on earth and also stands as the largest source of all-purpose water in Bangladesh. The higher concentrations of iron (Fe), manganese (Mn), and lead (Pb) in wat...
Evaluation of Heavy Metals in Drinking Water of Tribal Districts Ex-FATA Pakistan Authors
This study was conducted to evaluate the six heavy metals zinc (Zn), iron (Fe), copper (Cu), nickel (Ni), chromium (Cr), and cadmium (Cd) in seven water samples collected from seven tribal districts (Bajaur, Mohmand, Khy...
Removal of Cr6+ from Synthetic Polluted Water using Fe Modified Sugarcane Bagasse & Peanut shell Powder
Unprocessed waste is dumped in lakes and rivers which possess a severe environmental risk through heavy metal’s contamination within the food chain, especially chromium Cr6+. It applies for sustainable development goals...
Simulation for migration and treatment of groundwater contamination in coal mining subsidence area: A case study of Datong dump, Huainan, China
The liquid that seeps into the earth from landfills and removes garbage is called landfill leachate. Pollutants like organic and inorganic chemicals, xenobiotic substances, etc. are found in landfill leachate which conta...