Age as a risk factor for prostate diseases: A 6-year selective prospective study among males in the Brong Ahafo region of Ghana
Journal Title: The Journal of Medical Research - Year 2018, Vol 4, Issue 3
Abstract
Introduction: There are many contributing factors to the onset of prostate diseases. Major factors include age, race, hormonal, genetic influence and lifestyle. Diseases of the prostate are generally regarded as the diseases of elderly men. Despite the general attribution of prostate diseases to old age, some school of thought have propounded a polar view to this assertion. Objective: This study seeks to assess age as a risk-factor for prostate diseases among men in the Brong Ahafo Region of Ghana. Method: A selective prospective study was employed to review prostate cases from 2009 to 2014. Subjects were selectively recruited for the study using the reference age of the study location (40 yrs) – men from 40 years and above were eligible for testing. Patients were routinely screened for prostate lesions using positive family history, serum prostate specific antigen (PSA) test, digital rectal examination and ultrasound scan. Age, diagnosis and grading of carcinomas were also recorded for this study. Results: The age range of participants was 42- 101 years with a mean+ SD of 70.94 +10.008 and a higher incidence occurring in the year 2010. A higher number of prostatic lesions were recorded between the ages 60-89 with a modal prevalence at 70-89 years. About 51.78% of study participants were diagnosed with benign prostate hyperplasia, 40.07% with adenocarcinomas, 0.85% with chronic prostatitis and 7.3% for both prostatitis and benign prostate hyperplasia. Out of the 589 benign and malignant prostate lesions reviewed, well differentiated adenocarcinoma were prominent among men aged 60-79 years and absent among 40-59 year old’s and ≥ 80 years. Moderately differentiated adenocarcinoma was prevalent among individuals 40-99 years but absent among men older than 100 years. Contrary finding is the presence of poor differentiation from 100 years and above. Conclusion: Ghanaian men between the ages of 50 and 89 are highly predisposed to prostate diseases compared to those <50 years and >89 years. This observation may provide a rational for effective medical or preventive interventions especially among Ghanaian Adults.
Authors and Affiliations
AK Egote, PPS Ossei, E Agyeman-Duah, J Taylor
Keywords
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- EP ID EP531631
- DOI 10.31254/jmr.2018.43010
- Views 107
- Downloads 0
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