Age wise distribution of colorectal cancer: An institutional observational study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 1
Abstract
Background: Overall, the incidence of colorectal cancer appears to be stable or diminishing. However, based on our regional cancer institute’s datas, we have observed the increasing incidence of colorectal cancer in patients ≤40 age. The aim of this study was to verify the rising trend, clinico-pathological features and survival in colorectal cancer in patients ≤40,in comparison to patients >40 age. Materials and methods: A retrospective study was conducted to review all patients≤ 40 age and more than 40 year of age separatly with a diagnosis of colorectal cancer from January 2004 to December 2012. Results: Young patients were 24.17% of total 1096 colorectal cases. In young patients 60.37% were male and 39.63% were female. 9% young had family history & only 8% had history of alcohol intake. Onset of symptoms to reaching diagnosis period is longer in younger patients.(Range 3 months to 1 year in young, while 1 months to 6 months in older). Higher pathological T stage was seen in the younger age group when compared with patients above 40 years. Also the younger age group showed more advanced N stage when compared with patients above 40 years. With final TNM staging, in younger age group 66% were in stage IV and 30% were in stage III. Eighty percent of all young cancer deaths were within 22 months (from 8months to 22 months). Conclusion: Above results show the aggressive nature and late diagnosis of carcinoma colorectal in young. These data highlight a need for thorough evaluation of young with colorectal symptoms and in high risk population, also life style modification agenda by Govt .or non Govt. organization.
Authors and Affiliations
Pramila Kumari, Neeti Sharma, Praveen Kumar Khatri, Satya Narayan, Saroj Kumari, Kamlesh Kumar Harsh, Shankar Lal Jakhar, HS Kumar
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