Airborne fungi in Isfahan and evaluation of allergenic responses of their extracts in animal model
Journal Title: Jundishapur Journal of Microbiology - Year 2010, Vol 3, Issue 4
Abstract
Introduction and objective: Detection of the common allergen airborne fungi in any region is critical for prevention and treatment of allergic fungal diseases. Therefore, this study was conducted to identify the most common airborne fungal species of Isfahan, investigate their allergic reactions in animal and obtain local fungal strains for use as antigens in allergy tests to be used. Materials and methods: An open plate method was used to scan airborne fungal contents over 12 months in Isfahan. On the same days every week, triplicate samples were collected at three different locations in the morning, at noon and in the evening. The fungal culture media were incubated at 25ºC until growth appeared and then the airborne fungi were identified by routine mycological laboratory methods. The extracts of the most common airborne fungi isolated, were examined with skin prick test for allergic reactions in laboratory animals. Results: During this study, the most abundant airborne fungi identified in Isfahan were species of yeasts, yeast like (Candida spp., Geotrichum spp., and Trichosporon spp.), and mold (Cladosporium spp., Penicillium spp., Aspergillus spp., and Alternaria). Positive skin reactions were observed with Cladosporium spp.(40%), and Aspergillus spp. (21%), Alternaria spp. (17%), Penicillum spp. (15%) and Geotrichum spp. (7%). Conclusion: It is concluded that fungi have a significant role in infecting immunocompromised hosts, information obtained in the present study contribute toward a better understanding of the pattern of occurrence of airborne fungi, and may assist allergists, clinicians and epidemiologists to treat the diseases.
Authors and Affiliations
Mostafa Chadeganipour, Shahla Shadzi, Shahi Nilipour, Gholamreza Ahmadi
Keywords
Related Articles
- EP ID EP97046
- DOI -
- Views 181
- Downloads 0
Biological and immunological characteristics of Brucella abortus S99 major outer membrane protein
Introduction and objective: Outer membrane proteins (OMPs) of Brucella are considered as immunogenic structures which can be used to design and develop a subunit vaccine for human brucellosis. Brucella abortus S99 OMPs p...
Comparative study of current diagnostic method with clinical based method for brucellosis: presentation of diagnostic clinical criteria in limited resource area
Introduction and objectives: According to National Program against Brucellosis (NPB), diagnosis is based on serological tests (Wright>1/80 and 2 ME>1/20) in the presence of clinical finding. Regarding the lack of l...
Characterization of antibiotic resistant patterns of Salmonella serotypes isolated from beef and chicken samples in Tehran
Introduction and objective: Infection with Salmonella is the most frequently reported cause of bacterial food-borne illness worldwide. Raw meat samples are a common source and, in recent years, much attention has been fo...
Evaluation of antimicrobial effect of hops extracts on intramacrophages Brucella abortus and B. melitensis
Introduction and objective: Brucellosis is a zoonosis disease among animal and human, and has been endemic in Iran. The most important virulence factors of Brucella are related to their capability of intraphagocytic surv...
The antimicrobial potential of ten often used mouthwashes against four dental caries pathogens
Introduction and objective: Increasing number of people are using mouthwashes for general and oral health care. Few of these mouthwashes, however, have undergone rigorous testing, as evidenced by the limited amount of in...