Alteration of Some Vital Parameters in Saudi Smokers
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 1
Abstract
Background: There are a wide range of mutagens and carcinogens in cigarette smoke including polycyclic aromatic hydrocarbons, aromatic amines and aldehydes. These reactive substances induce cellular oxidative damage. Objective: The current study aims to investigate the effect of cigarettes smoking on some immunological and oxidative markers in Saudi healthy smokers. Subjects and Methods: The study was conducted on 30 male healthy cigarette smokers with mean age±SD of 25±4 years, in addition to healthy non-smokers with the same age group. Total leucocytic count, plasma immunoglobulin G (IgG) and complement 3 (C3) levels were determined. Also, plasma activities of catalase (CAT) and superoxide dismutase (SOD) were estimated. Results: The study showed significant decreases in the activities of antioxidant enzymes as compared to non-smoker. Moreover, results illustrated that the levels of IgG and C3 were markedly reduced in cigarette smokers when compared to those of non-smokers. Conclusion: Cigarettes smoking induces the inflammatory reactions in the human body.
Authors and Affiliations
Tarek Salem, Alwaleed M Almejlad, Muhammad H Alharbi, Sultan E Almalik, Sulaiman S Alharbi, Abdullah S Alshammari, Sultan T Almutrafi, Abdullah H Alharbi
Keywords
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- EP ID EP541664
- DOI 10.21276/ijmrp.2017.3.1.018
- Views 71
- Downloads 0
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