Alterations in Some Biochemical Parameters and Trace Elements in Asthmatic Patients in Owerri
Journal Title: Journal of Krishna Institute of Medical Sciences University - Year 2017, Vol 6, Issue 2
Abstract
Background: Asthma is a chronic disease characterized by recurrent cough and wheeze. Aim and Objectives: To determine the level of some biochemical parameters and trace elements in asthmatic patients attending General Hospital Owerri. Material and Methods: Thirty six confirmed asthmatic patients and thirty six apparently healthy subjects (control) between the age of 10 to 30 years were selected in this study. Serum trace elements: Zinc and copper, malondialdehyde, vitamin C, vitamin E, immunoglobulin A and immunoglobulin E were estimated using standard methods. Results: There serum levels of copper, IgE, IgA and MDA were significantly increased in asthmatic patients when compared to control (p<0.05). While the serum levels of zinc, vitamin C and vitamin E were significantly decreased in asthmatic patients when compared with the control (P< 0.05). Conclusion: These observations probably indicated that asthmatic patients could be prone to the oxidative stress. Also, foods or diets containing antioxidants could be beneficial to asthmatic patients.
Authors and Affiliations
Nnodim Johnkennedy, Nwadike Constance, Nwobodo Emmanuel, Edward Ukamaka, Aloy-Amadi Oluchi, Onah Christian
Keywords
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