An analysis of risk factors for Multidrug Resistant Tuberculosis (MDR-TB): a hospital-based study
Journal Title: Journal of Public Health and Development - Year 2023, Vol 21, Issue 2
Abstract
Multidrug Resistant Tuberculosis (MDR-TB) is the world's most serious problem and one of the leading causes of death. Because of its difficult diagnosis, high rates of treatment failure, and death, MDR-TB is a new challenge in TB control programs. The study aims to identify and analyze the risk factors of Multidrug Resistant Tuberculosis (MDR-TB). The study used a case control study design and was conducted at the Labuang Baji Hospital in Makassar City, Indonesia. The sample was 140 people consisting of 70 in the case group and 70 in the control group. Purposive sampling was used to collect the data. Data were analyzed using STATA program with Multiple Logistic Regression. Significant risk factors of Multidrug Resistant Tuberculosis (MDR-TB) were duration of treatment (OR= 5.655 [Cl 95%: 2.507-12.999]; p<0.001), previous treatment history (OR= 4.833 [Cl 95%: 2.092-11.525]; p<0.001), PMO factor (OR= 3.106 [Cl 95%: 1.227-8.338]; p=0.008), compliance with drugs (OR= 10.961 [Cl 95%: 4.640-26.40]; p<0.001), drug side effects (OR=2.521 [Cl 95%: 1.070-6.126]; p=0.020) and protective factor is the complexity of drug regimen (OR= 0.329 [Cl 95%: 0.136-0.768]; p=0.005). It can be concluded that compliance with drugs is a dominant risk factor for MDR-TB. Improved TB control programs by monitoring the treatment of patients who experienced treatment failure (dropout) probably will increase treatment adherence and cut off MDR-TB transmission.
Authors and Affiliations
Sri Wahyuningsih, Andi Zulkifli, A. Arsunan Arsin, Ansariadi, Sudirman Nasir, Masyita Muis, Andi Agus Mumang
Keywords
Related Articles
- EP ID EP718602
- DOI 10.55131/jphd/2023/210208
- Views 67
- Downloads 0
Effectiveness of salt and ginger water soaking on pain scale in elderly people suffering from gout
High uric acid levels cause an increase in needle-shaped uric acid crystals, especially in joints, which can cause pain. This study aimed to determine the effectiveness of saltwater and ginger water soaking in reducing t...
Assessing inequalities in the hypertension management under national health insurance: Evidence from Southern Central Java, Indonesia
Equal access to disease management is crucial to control the impact of hypertension on the burden of disease in Indonesia. This study aimed to assess the extent of inequalities in the use, quality, and outcomes of hypert...
Counseling intervention on iron-folic acid adherence and clinical outcomes among pregnant women and women planning to be pregnant: a scoping review
Anemia during pregnancy is a major health problem that affects 25-50% of the world's population and around 50% of pregnant women. One of the causes of stunting is Low Birth Weight, which most often occurs in mothers who...
Effect of the oral health care program (FUNDEE) on the oral health care behavior status of elderly ethnic groups living in rural areas: a quasi-experimental study
The oral health of elderly people plays a major role in their overall health and quality of life and is an integral part of personal care. The aim of this study was to evaluate the effect of implementing the oral health...
Evaluation of binge drinking behavior among working-age populations in Thailand using GIS: A national survey in 2017
This study identifies the prevalence of binge drinking behaviour and the statistical relationship between local patterns and binge drinking behaviour among the working-age population in Thailand. This study was conducted...