An assessment of liver function test in typhoid fever in children
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2016, Vol 3, Issue 4
Abstract
Background: Liver involvement is common in typhoid and may be in the form of hepatomegaly, jaundice, biochemical and histopathological changes. Isolated hepatomegaly is of no clinical significance, but its occurrence with jaundice though rare indicates liver involvement as a result of generalized toxemia or invasion by salmonella. Significant liver damage may have occurred without obvious clinical signs or abnormal laboratory tests. Aim of study: Assessment of liver functionin typhoid fever in children diagnosed by widal agglutination test by biochemical test. Setting: Fifty four cases of typhoid fever less than 16 years admitted inPaediatric Department MY Hospital, MGM Medical College Indore, comprised the clinical material for the study. Design: Cross sectional study. Method: 54 children with enteric fever were taken after making clinical diagnosis, confirmed by Widaltest and LFT was performed to assess liver involvement. Result: Hepatomegaly was seen in 19[35%] cases and tender hepatomegaly was seen in 2 cases of the study group. S.G.O.T was raised in 27[50%] cases and S.G.P.T was raised in 25 [46%] cases out of total 54 cases. Most of the cases with raised S.G.O.T and S.G.P.T presented in the 2nd week of fever. Serum bilirubin was raised in only 2 cases. Conclusion: hepatic involvement is common in typhoid fever. Typhod hepatitis should be diagnosed and manage accordingly.
Authors and Affiliations
Hemant Jain, Sunil Arya, Virendra Xess
Keywords
Related Articles
- EP ID EP224131
- DOI 10.17511
- Views 146
- Downloads 0
Patent ductus arteriosus – clinical profile and outcome after treatment in a tertiary care hospital
Background: Patent ductus arteriosus (PDA) is the commonest congenital heart disease seen in neonatal ICU. Methods: A prospective observational study was conducted in the neonatal intensive care unit of Vydehi institute...
Screening of young children between 2-24 months of Age with a first febrile UTI for VUR with imaging modalities
Background: Urinary tract infection (UTI) is one of the most common serious bacterial illnesses affecting children. The presence of moderate to severe vesicouretheral reflux (VUR), particularly if bilateral, is an import...
Prognostic significance of total platelet count with PICU outcome
Background: Platelets in addition to their contribution in hemostasis are inflammatory cells having important role in host defense and can be of prognostic significance. Aim: Present study aims to evaluate the relationsh...
A study on the types of dehydration and serum sodium level in infants and young children at the time of hospital admission with acute diarrhea in rural area of Jharkhand
Objectives: This study was done to know the incidence of different type of dehydration clinically in acute watery diarrhea (mild, moderate and severe) along with serum sodium level (isonatraemic, hyponatraemic, hypernatr...
Management of space in the mixed dentition: The use of lip bumper
Management of dental space problems continues to play a substantial role in interceptive orthodontics. In the mixed dentition, moderate crowding problems can be resolved through preservation of the Leeway space, regainin...