An evaluation of tear film and ocular surface changes in type 2 diabetes mellitus
Journal Title: International Journal of Allied Medical Sciences and Clinical Research - Year 2016, Vol 4, Issue 4
Abstract
Aim To compare tear film changes and ocular surface abnormalities in diabetics with that in non-diabetics. Materials & methods In this prospective case control study 100 eyes of 50 patients with Type 2 diabetes and 100 eyes of 50 normal patients were compared. All the patients were subjected to tear assessment tests- Schimers tests, Tear break up time tests in addition to Corneal sensitivity tests, CCT and CIS. Conclusion Our study showed that In Diabetics CCT was 560.14(SD 15.65) and Non diabetics was 534.14(SD 44.50) p value < 0.005.Corneal sensitivity measured by Cochet-Bonnet esthesiometer in diabetics was 26.08+/- 5.14mm and in Non diabetics was 53.58+/-2.06mm(p value <0.001).Tear break up time in diabetics was 6.8 +/-7.01 sec and in non-diabetics was 12.8+/-5.71sec(p value< 0.001).Total secretion by Schimers test was 7.77+/-3.9mm and basal secretion was 13.4+/-5.7mm(p value<0.001) . Conjunctival impression cytology revealed squamous metaplasia in diabetics as 1.25+/-0.63mm and in non-diabetics 0.65+/-0.57mm .Goblet cell density in diabetics was 429.68+/-108.35 cells/mmsq and in non-diabetics was 545.17+/-77.56cells/mmsq. Therefore diabetic patients with poor metabolic control and diabetic retinopathy should be assessed for tear film and ocular surface changes.
Authors and Affiliations
AarthiPanneerselvam .
Keywords
Related Articles
- EP ID EP420073
- DOI -
- Views 53
- Downloads 0
Controlled release matrix drug delivery system – a review
Oral controlled release drug delivery system becomes a very promising approach for those drugs that are given orally but having the high dosing frequency and shorter half life. Matrix tablets serves as an important tool...
Study of carotid intima media thickness in patients of Non diabetic chronic kidney disease
Background Patients with chronic kidney disease are at high risk for developing cardiovascular complications. Cardiovascular diseases are major cause of morbidity and mortality in patients of chronic kidney disease due t...
Diabetes vs silent killer: Magnitude and allied factors of hypertension among diabetic patient at hidar 11 hospital, Akesta, Ethiopia
Background Hypertension is a masked silent killer and one of the perilous non-communicable diseases. Hypertension and diabetes generally coexist because they share similar risk factors, including being overweight, follow...
Viruddhahara and its role in formation of disease
Viruddha Ahara are those food articles which is composed of substances having no affinity at all and which vitiates the Doshas (Morbid Humors) but do not eliminate them from our body. They are of 18 types of Viruddha Aha...
Immediate effect of ACU-TENS over non acupuncture points in chronic obstructive pulmonary disease patients
What is the immediate effect of Acu-TENS over non acupuncture points on reduction of dyspnoea and PEFR in patients with Chronic Obstructive Pulmonary Disease? In India COPD is 2nd most common disorder after pulmonary tub...