An Investigation into the Pattern of Antibiotic Resistance of Bacteria Causing Ventilator – Associated Pneumonia in ICU
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2017, Vol 19, Issue 7
Abstract
Aims: The present study sought to determine the pattern of antibiotic resistance of pathogens in Ventilator–Associated Pneumonia (VAP) and to investigate risk factors of multi-drug resistant (MDR) in ICUs of tertiary referral hospitals. Study Design: Cross sectional study. Place and Duration of Study: In this cross sectional study, the files of 196 patients with VAP hospitalized in ICU of tertiary referral hospitals in 2014 were examined. Methodology: In order to determine common pathogens and their pattern of antibiotic resistance, the patients’ results of culturing Bronchoalveolar fluid were examined. The agent pathogens were divided in two groups of with and without MDR and different demographic and risk factors for resistance were compared into the two groups. Results: Among from 196 patients examined, 53 and 143 cases had early and late pneumonia, respectively. There was no significant difference between the early and late groups in regard to the frequency of MDR pathogens. There was no significant difference between the two groups with and without MDR in terms of age, gender, immune deficiency, duration of hospitalization and taking antibiotics. The most common early and late types were Acinetobacter baumannii (40.4%) and Klebsiella pneumoniae (31.8%), respectively and the minimal resistance of the bacteria was related to Colistin and amikacin antibiotics. Conclusion: Considering the high and increasing prevalence of antibiotic resistance, measures such as providing samples for culture before prescribing antibiotics, starting empirical treatment based on the frequency of agent pathogens and the rate of their antibiotic resistance and avoiding prescription without indication of antibiotics seem necessary.
Authors and Affiliations
Babak Alikiaii, Taghi Hashemi, Omid Aghadavoudi, Nasim Emami
Keywords
Related Articles
- EP ID EP311256
- DOI 10.9734/BJMMR/2017/30487
- Views 77
- Downloads 0
Can Selenite be an Ultimate Inhibitor of Ebola and Other Viral Infections?
It is known that the virulence of Ebola and other RNA enveloped viruses involves in the first step their attachment to host cell membranes. Following this initial step the virus enters the target cell cytoplasm by formin...
Role of Hypertension as a Major Risk Factor of Stroke in Africa; Libya: Community Based Survey
Hypertension is a very common medical disorder and a major health problem in North Africa. Hypertension is associated with an increase in the risk of stroke and hospitalization. Objectives: To estimate the importance of...
Direct Esthetic Resin Restorations of Anterior Coronal Fractures: A Case Report
Replacing tooth structure that is lost due to trauma to the anterior teeth remains a challenge to the restorative dentist. The restorations must not only be able to withstand masticatory forces and stress but also be est...
Effect of the Sampurna Hriday Shuddhikaran (SHS) Model in Heart Failure Patients in India: A Prospective Study
Background and Objectives: Chronic heart failure (CHF) is an increasingly widespread, costly and deadly disease, frequently named as an epidemic of the 21st century. Herbal treatments may provide promising & beneficial t...
Assessment of Birth Preparedness and Complication Readiness (BP/CR) among Pregnant Women in Orlu Local Government Area of Imo State, Nigeria
Birth Preparedness and Complication Readiness (BP/CR) are very important tenets of Focused Ante-Natal Care (FANC) aimed at reducing maternal morbidity and mortality. This study assessed birth preparedness and complicatio...