AN OBSERVATIONAL STUDY ON ANTI-THYROPEROXIDASE ANTIBODY POSITIVITY IN THYROIDITIS CASES AMONG ADULTS IN A TERTIARY CARE CENTER
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 13
Abstract
BACKGROUND The major cause of hypothyroidism in adults is Hashimoto thyroiditis. Thyroperoxidase (TPO) is an enzyme involved in thyroid hormone synthesis. And anti-TPO antibodies are raised in cases of Hashimoto’s thyroiditis. We wanted to study the incidence of anti-TPO antibody positivity in thyroiditis cases. MATERIALS AND METHODS All the patients attending surgery OPD from Jan. 2016 to Dec. 2016 who were FNAC proven cases of Hashimoto thyroiditis were selected and sent for anti-TPO antibody positivity and the proportion of patients with positive result were compared according to their thyroid functional status using various statistical methods. RESULTS It was an observational study and the idea was to see the accuracy with which the FNAC finding of thyroiditis correlated with antiTPO antibody positivity. And we also looked for thyroid function status of all the patients. Comparison was done of each group in relation to thyroiditis and anti-TPO antibody positivity. 97% thyroiditis cases were positive for anti-TPO antibody. CONCLUSIONS The test for anti-TPO antibody positivity can be used to detect cases of Hashimoto’s thyroiditis with 97% certainty. The anti-TPO antibody testing can be used along with regular testing of TFT, FNAC in cases of thyroiditis
Authors and Affiliations
Aneesha Fathima T. S, Shajahan Y.
Keywords
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- EP ID EP555730
- DOI 10.14260/jemds/2019/223
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