An Observational Study to Compare Dexmedetomidine and Clonidine as Adjuvant to Local Anaesthetic Ropivacaine (0.5%) in Supraclavicular Brachial Plexus Block for Upper Limb Surgery
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2018, Vol 5, Issue 4
Abstract
Context: Various adjuvants have been used with Ropivacaine in supraclavicular blocks to enhance sensory and motor block along with prolongation of postoperative analgesia. Aim: To compare the effect of dexmedetomidine and clonidine as adjuvant to 0.5% ropivacaine in supraclavicular brachial plexus block with respect to onset and duration of sensory and motor block and duration of analgesia. Methods and Material: After ethical committee’s approval, a prospective randomised study of 60 patients aged18-60 years were randomly divided into two groups (Group C and Group D) of 30 each. Group C received 50mcg clonidine with ropivacaine (29ml), Group D received 50mcg dexmedetomidine with ropivacaine (29ml), via supraclavicular approach. Onset and duration of sensory and motor block and duration of analgesia in both groups were evaluated. Intraoperative hemodynamics and adverse effects were observed. Statistical Analysis: Numerical-variables were presented as mean & standard-deviation while categorical-variables were presented as frequency and percent. For analysis, unpaired student t-test and chi-square test were used. Results: Early onset and prolonged duration of sensory and motor block and prolonged duration of analgesia was seen in group D, as compared to group C. Conclusion: Dexmedetomidine produces rapid onset and prolonged duration of sensory and motor block and also prolonged duration of analgesia with good hemodynamic stability with no side effects as compared to clonidine.
Authors and Affiliations
Priyanka Singla
Keywords
Related Articles
- EP ID EP535619
- DOI 10.21088/ijaa.2349.8471.5418.16
- Views 86
- Downloads 0
Effect of use of oral Pregabalin as an adjunct in Spinal Anaesthesia
Pain relief with minimal side effect in post operative surgical patients is essential for early mobility and recovery. Objective: This study was conducted to find out whether preoperatively oral pregabalin used as an adj...
Comparative Study between Intrathecal Dexmedetomidine and Intrathecal Magnesium Sulphate as an Adjunct to Bupivacaine in Spinal Anesthesia for Lower Limb Orthopaedic Surgeries
Introduction: In order to maximize quality of anesthesia and effective analgesia, a number of adjuvants have been added to intrathecal local anesthetics but none of them have yet been identified without any adverse event...
Chronic Knee Osteoarthritis: Intra - articular Sodium Hyaluronic Acid and Radiofrequency Neurotomy of Genicular Nerve
Background: Various modalities have been used for treatment of chronic knee osteoarthritis but with limited benefits. Radiofrequency neurotomy of genicular nerve is emerging as newer modality for pain relief with few com...
Awareness of Operation Theatre and ICU Nurses about Pharmacovigilance: A Questionnaire Based Study
Background & Aim of the Study: The main objective of the Pharmacovigilance programme of India is to create a nationwide system of adverse drug reporting by health care professionals and patients. Nurses are the most esse...
Evaluation of Dexmedetomidine as an Additive to Ropivacaine for Popliteal Approach for Sciatic Nerve Block for Foot Surgeries
Introduction: Peripheral nerve blocks are used in varieties of surgical and diagnostic procedures. Various methods or approaches have been tried to prolong the duration of nerve blocks. Dexmedetomidine acts selectively o...