AN OVERVIEW OF CATARACT ACTIVITY AND THEIR SCREENING METHODS
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2018, Vol 8, Issue
Abstract
A cataract is a clouding of the lens in the eyes which leads to a decrease in vision. Cataracts often develop slowly and can affect one or both eyes. Cataracts are the cause of half of the blindness and 33% of visual impairement worldwide. Cataract is a multifactorial disease associated with several risk factors such as aging, diabetes, malnutrition, diarrhoea, poverty, sunlight, smoking, hypertension and renal failure. Various convenient models are available for the evaluation of drugs for the prevention of cataract formation they are galactose induced cataracts in rats, naphthalene induced cataracts in rats, selenite induced cataract in rats etc. Various medicinal plants having anti-cataract activity were reported with minimal adverse effects. Even there is the need to find out novel drug with minimal adverse effects to treat the cataract activity and to prevent the blindness in humans.
NEEDLELESS INJECTION SYSTEM: AN OVERVIEW
Abstract Needle-less injections are designed to solve the problem associated with hypodermic needle injection. Needle-less injection system was first introduced by Marshell Lockhart in1936. Needle-less system is based on...
Studies on phytochemical analysis and antimicrobial activity of Artocarpus communis fruit latex against selected pathogenic microorganisms
The latex is widely used in cosmetics, pharmaceuticals and food industry as in paper, textile and petroleum industries also. The present study was carried out to assess the potential antimicrobial activity of methanolic,...
LIQUID CHROMATOGRAPHY MASS SPECTROMETRIC METHOD FOR QUANTIFICATION OF POTENTIAL GENOTOXIC IMPURITY 2, 6-DIAMINOPYRIDINE IN MINODRONIC ACID
Abstract A new, simple, accurate and sensitive method was developed for the quantification of potential genotoxic impurity 2, 6-Diaminopyridine in Minodronic acid using Liquid Chromatographic Mass Spectrometry (LCMS). Th...
COMPARATIVE INVESTIGATION OF ANTIDIABETIC ACTIVITY OF ACARBOSE, MIGLITOL AND SALACIA OBOLNGA IN PATIENTS OF TYPE 2 DIABETES MELLITUS
Acarbose, Miglitol and Voglibose are the marketed ?-glucosidase inhibitor used to reduce post prandial glucose level in the patients of type 2 diabetes mellitus. Increased post prandial blood is cause of number of diseas...
GASTRORETENTIVE MUCOADHESIVE MICROSPHERE: A REVIEW
The current article focuses on the principles of mucoadhesive drug delivery systems based on adhesion to biological surfaces that are covered by mucus. In recent years scientific and technological advancements have been...