Analgesic and anti-Inflammatory activity of Tradescantia fluminensis leaves extract
Journal Title: The Journal of Phytopharmacology - Year 2017, Vol 6, Issue 1
Abstract
Objective: The present study sought to evaluate the anti-inflammatory and analgesic activities of ethanolic extract from Tradescantia fluminensis leaves. Methods: The crude leaf extract of T. fluminensis was investigated for anti-inflammatory and analgesic activities in Wistar Albino rats and mice respectively. The anti-inflammatory activity was investigated using egg albumin induced oedema model while acetic acid and formalin-induced paw licking models were used to evaluate the analgesic activity. Results: The extract showed a significant (P<0.05) dose-dependent inhibition of inflammation and pain compared to the control group. Conclusion: The leaf extract possesses anti-inflammatory and analgesic activities. The activities could be attributed to phytochemicals present in the plant.
Authors and Affiliations
Wilson Rwai Waweru, Lawrence Obado Osuwat, Connie Wambui Mureithi
Keywords
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