Analyses of Plasmids Harbouring Quinolone Resistance Determinants in Enterobacteriaceae Members

Journal Title: Polish Journal of Microbiology - Year 2017, Vol 66, Issue 4

Abstract

The aim of this study was to explore the plasmid characteristics of eight clinical Enterobacteriaceae strains containing extended broad spectrum beta-lactamases and plasmid-mediated quinolone resistance. Plasmids were transferred by conjugation or transformation and resistance determinants were investigated by PCR. We showed that at least one plasmid harbouring qnrB or qnrS determinant was transferred by conjugation in five isolates. QepA determinant was confirmed to be on a non-conjugative plasmid. We found at least one beta-lactamase gene in seven of the eight clinical isolates having plasmid-mediated quinolone resistance, which indicated that these two resistance determinants were mostly on the same conjugative plasmids.

Authors and Affiliations

Bayri Erac, Fethiye Ferda Yilmaz, Ismail Ozturk, Sabire Sohret Aydemir, Mine Hosgor-Limoncu

Keywords

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  • EP ID EP245135
  • DOI 10.5604/01.3001.0010.7084
  • Views 87
  • Downloads 0

How To Cite

Bayri Erac, Fethiye Ferda Yilmaz, Ismail Ozturk, Sabire Sohret Aydemir, Mine Hosgor-Limoncu (2017). Analyses of Plasmids Harbouring Quinolone Resistance Determinants in Enterobacteriaceae Members. Polish Journal of Microbiology, 66(4), 529-532. https://europub.co.uk./articles/-A-245135