Analysis of Dinucleotide Bias and Genomic Signatures Across Cyanobacterial Genomes
Journal Title: JOURNAL OF ADVANCES IN BIOTECHNOLOGY - Year 2013, Vol 3, Issue 3
Abstract
Dinucleotide relative abundance or frequency of dinucleotides in particular nucleotide sequence is reported as genomic signature as it is specific across different DNA samples and able to identify the variance among different groups whereas identical or similar for closely related organisms. Dinucleotide relative abundance value is identified to be overall constant due to numerous factors as dinucleotide stacking energy and DNA helicity, mechanisms of replication, repair and context-dependent mutation pressures and includes information about genome-wide processes. In this study, we analyzed genome sequence of 41 cyanobacteria to gain an insight of dinucleotide bias in their genomes. Across different dinucleotides, TA is broadly underrepresented followed by CG and then AC+GT whereas; AA+TT and GC occupied a major portion of dinucleotide distribution across all cyanobacterial genomes. Underrepresentation of TA seems to be influenced by GC-content of the members as it tends to decrease when there is an increase in GC content. Members with similar GC content possess similar pattern of genomic signature. Habitats also seem to influence the dinucleotide relative abundance values of the organisms because it is suggested that marine organisms.
Authors and Affiliations
Dhananjaya P. Singh, Ratna Prabha
EFFECTS OF BLENDING RICE BRAN OIL BIODIESEL with diesel ON THE PROPERTIES OF
Some properties of rice bran oil and the biodiesel such as saponification value and iodine value even when within standard limits can be more effective if reduced further. One way of achieving this is to blend with diese...
Strategies and Approaches for Antibiotic Yield Improvement in Actinomycetes
Actinomycetes represent a valuable source of commercially significant antibiotics. However, the yields of antibiotics in wild Actinomycetes usually could not meet the commercial needs and so antibiotics yield improvement...
Secondary multiplication of somatic embryos in banana (Musa spp. AAA) in semisolid medium: effect of the culture vessel type and sterilization method
The objective of this work was to evaluate the influence of the type of culture vessel, and sterilization method on secondary multiplication of somatic embryos of the banana cultivar Grande naine (AAA) in semisolid cul...
CELL SURFACE PROPERTIES OF HALOTOLERANT PROBIOTIC LACTOBACILLI
Cell surface characteristics of two halotolerant commercial probiotics (Lactobacillus casei Shirota and L. plantarum 299v) and three halotolerant potential probiotics (L. plantarum, L. pentosus and L. acidipiscis) isolat...
2G Ethanol Production From Palm Lignocellulosic Biomass
Brazil presents the world's largest potential for the production of palm oil due to nearly 75 million hectares of land suitable for palm culture and advantageous soil and climate. The biomass generated in the pro...